Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 8/20 | 0.67 |
| ▸ | IL1B | P01584 | 10/20 | 0.50 |
| ▸ | TNF | P01375 | 1/20 | 0.45 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833946 | 0.84 | NLRP3 (0.55) | NLRP3IL1BTNFCHEK2 | |
| SCHEMBL31057144 | 0.84 | IL1B (0.68) | NLRP3IL1BTNFCHEK2 | |
| Hydrochloric Acid SCHEMBL31057159 | 0.83 | IL1B (0.67) | NLRP3IL1BTNFCHEK2 | |
| SCHEMBL29307453 | 0.83 | IL1B (0.59) | NLRP3IL1BTNF | |
| SCHEMBL26938877 | 0.80 | NLRP3 (1.00) | NLRP3IL1B | |
| SCHEMBL26938054 | 0.80 | NLRP3 (1.00) | NLRP3IL1B | |
| SCHEMBL24575029 | 0.80 | NLRP3 (1.00) | NLRP3IL1B | |
| SCHEMBL29696947 | 0.80 | NLRP3 (1.00) | NLRP3IL1B | |
| SCHEMBL31681900 | 0.80 | NLRP3 (0.54) | NLRP3IL1BTNF | |
| SCHEMBL24575315 | 0.80 | IL1B (0.72) | NLRP3IL1BTNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022135567-A1 | PYRIDAZINE-CONTAINING COMPOUND AND MEDICINAL USE THEREOF | 上海拓界生物医药科技有限公司 | 2022-06-30 | — | — | WO | disclosed |