Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 10/20 | 0.54 |
| ▸ | IL1B | P01584 | 12/20 | 0.50 |
| ▸ | TNF | P01375 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833946 | 0.86 | NLRP3 (0.55) | NLRP3IL1BTNF | |
| SCHEMBL31057144 | 0.84 | IL1B (0.68) | NLRP3IL1BTNFPIM1 | |
| Hydrochloric Acid SCHEMBL31057159 | 0.83 | IL1B (0.67) | NLRP3IL1BTNFPIM1 | |
| SCHEMBL29307453 | 0.83 | IL1B (0.59) | NLRP3IL1BTNFPIM1 | |
| SCHEMBL31681895 | 0.83 | NLRP3 (0.73) | NLRP3IL1B | |
| SCHEMBL31681927 | 0.81 | IL1B (0.70) | NLRP3IL1BTNF | |
| SCHEMBL24575705 | 0.80 | NLRP3 (0.67) | NLRP3IL1BTNF | |
| SCHEMBL30833869 | 0.78 | IL1B (0.51) | NLRP3IL1BTNFPIM1 | |
| SCHEMBL30834025 | 0.78 | IL1B (0.51) | NLRP3IL1BTNFPIM1 | |
| SCHEMBL31681932 | 0.74 | NLRP3 (0.66) | NLRP3IL1BTNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4613749-A1 | NLRP3 INFLAMMASOME INHIBITOR AND USE THEREOF | TransThera Sciences (Nanjing), Inc. (CN) | 2025-09-10 | — | — | EP | disclosed |