Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL1B | P01584 | 14/20 | 0.59 |
| ▸ | NLRP3 | Q96P20 | 8/20 | 0.59 |
| ▸ | TNF | P01375 | 1/20 | 0.56 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31057144 | 0.93 | IL1B (0.68) | IL1BNLRP3TNFPIM1 | |
| Hydrochloric Acid SCHEMBL31057159 | 0.92 | IL1B (0.67) | IL1BNLRP3TNFPIM1 | |
| SCHEMBL31681900 | 0.83 | NLRP3 (0.54) | IL1BNLRP3TNFPIM1 | |
| SCHEMBL24575705 | 0.83 | NLRP3 (0.67) | IL1BNLRP3TNF | |
| SCHEMBL30833946 | 0.81 | NLRP3 (0.55) | IL1BNLRP3TNF | |
| SCHEMBL30519335 | 0.81 | IL1B (0.57) | IL1BNLRP3TNFPIM1 | |
| SCHEMBL25249164 | 0.81 | IL1B (0.57) | IL1BNLRP3TNFPIM1 | |
| SCHEMBL29307331 | 0.79 | IL1B (0.61) | IL1BNLRP3TNF | |
| SCHEMBL29307307 | 0.79 | IL1B (0.58) | IL1BNLRP3TNF | |
| Hydrochloric Acid SCHEMBL31057201 | 0.77 | IL1B (0.67) | IL1BNLRP3TNFPIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148029-A2 | ORGANIC COMPOUNDS AS NLRP3 INHIBITORS | KODIAK SCIENCES INC. (US) | 2024-07-11 | — | — | WO | disclosed |