Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 2/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24576902 | 0.91 | NR3C1 (0.32) | NR3C1P2RX7 | |
| SCHEMBL24577968 | 0.81 | IKBKE (0.35) | NR3C1 | |
| SCHEMBL29760011 | 0.81 | IKBKE (0.35) | NR3C1 | |
| SCHEMBL24577656 | 0.81 | NR3C1 (0.35) | NR3C1P2RX7 | |
| SCHEMBL29759921 | 0.77 | NR3C1 (0.34) | NR3C1P2RX7 | |
| SCHEMBL24577986 | 0.77 | NR3C1 (0.34) | NR3C1P2RX7 | |
| SCHEMBL24577107 | 0.77 | NR3C1 (0.33) | NR3C1 | |
| SCHEMBL24577992 | 0.76 | IKBKE (0.42) | — | |
| SCHEMBL29759860 | 0.74 | NR3C1 (0.31) | NR3C1 | |
| SCHEMBL29759558 | 0.73 | HDAC2 (0.32) | NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022136509-A1 | PYRAZOLOTHIAZOLE CARBOXAMIDES AND THEIR USES AS PDGFR INHIBITORS | ACTELION PHARMACEUTICALS LTD (CH) | 2022-06-30 | — | — | WO | disclosed |