Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24577563 | 0.84 | KIT (0.40) | PTGS1PTGS2 | |
| SCHEMBL24576968 | 0.82 | BRD4 (0.41) | PTGS1PTGS2 | |
| SCHEMBL24578202 | 0.75 | CDC7 (0.35) | PTGS1PTGS2 | |
| SCHEMBL24578249 | 0.74 | KDM4E (0.43) | — | |
| SCHEMBL24577992 | 0.74 | IKBKE (0.42) | — | |
| SCHEMBL24577338 | 0.71 | HDAC6 (0.39) | — | |
| SCHEMBL24578329 | 0.70 | MAPT (0.30) | — | |
| SCHEMBL24576870 | 0.70 | MKNK1 (0.41) | — | |
| SCHEMBL24578808 | 0.70 | HDAC6 (0.39) | PTGS1PTGS2 | |
| SCHEMBL24578161 | 0.69 | RAB9A (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022136509-A1 | PYRAZOLOTHIAZOLE CARBOXAMIDES AND THEIR USES AS PDGFR INHIBITORS | ACTELION PHARMACEUTICALS LTD (CH) | 2022-06-30 | — | — | WO | disclosed |