Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CSF1R | P07333 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24580297 | 0.86 | MAOA (0.33) | ALDH1A1GAASMN1; SMN2ACHEMAOA | |
| SCHEMBL24579434 | 0.74 | ADRA1D (0.31) | SMN1; SMN2CSF1R | |
| SCHEMBL24580175 | 0.72 | CYP3A4 (0.43) | ALDH1A1SMN1; SMN2MAOAMAOBCYP3A4 | |
| SCHEMBL24579545 | 0.72 | CSF1R (0.42) | CSF1R | |
| SCHEMBL24580574 | 0.71 | MEN1 (0.44) | ALDH1A1GAASMN1; SMN2CYP3A4 | |
| SCHEMBL24580573 | 0.70 | PLK1 (0.48) | ALDH1A1GAASMN1; SMN2CYP3A4 | |
| SCHEMBL13998649 | 0.69 | ADRA1D (0.50) | ALDH1A1MAOAMAOBCYP3A4 | |
| SCHEMBL24576229 | 0.66 | CSF1R (0.54) | CSF1R | |
| SCHEMBL20021303 | 0.66 | POLB (0.33) | — | |
| SCHEMBL5305762 | 0.65 | CYP3A4 (0.51) | ALDH1A1SMN1; SMN2ACHECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022140528-A1 | DEUTERATED COLONY STIMULATING FACTOR-1 RECEPTOR (CSF-1R) INHIBITORS | GENZYME CORPORATION (US) | 2022-06-30 | — | — | WO | disclosed |