Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2796317 | 0.79 | PLK1 (0.74) | PLK1MAPTKMT2AHSD17B10TDP1 | |
| SCHEMBL1464754 | 0.79 | PLK1 (0.57) | PLK1MAPTKMT2AALDH1A1CYP3A4 | |
| SCHEMBL642237 | 0.78 | ABCB1 (0.46) | MAPTKMT2AHSD17B10TDP1ALDH1A1 | |
| SCHEMBL18114479 | 0.76 | RAB9A (0.49) | MAPTKMT2ATSHRHSD17B10ALOX15 | |
| SCHEMBL24580175 | 0.75 | CYP3A4 (0.43) | KMT2AALDH1A1CYP3A4MEN1SMN1; SMN2 | |
| SCHEMBL24580297 | 0.73 | MAOA (0.33) | PLK1MAPTTSHRTDP1ALDH1A1 | |
| SCHEMBL24580449 | 0.70 | ALDH1A1 (0.32) | ALDH1A1CYP3A4GAASMN1; SMN2 | |
| SCHEMBL12538439 | 0.70 | PLK1 (0.43) | PLK1MAPTKMT2ATSHRTDP1 | |
| SCHEMBL13998649 | 0.69 | ADRA1D (0.50) | KMT2ATSHRHSD17B10ALDH1A1KDM4E | |
| SCHEMBL643597 | 0.68 | KDM4E (0.49) | MAPTKMT2AHSD17B10ALOX15TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022140528-A1 | DEUTERATED COLONY STIMULATING FACTOR-1 RECEPTOR (CSF-1R) INHIBITORS | GENZYME CORPORATION (US) | 2022-06-30 | — | — | WO | disclosed |