Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 6/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2458357 | 1.00 | SMN1; SMN2 (0.45) | SMN1; SMN2LMNAMAPTHTTKMT2A | |
| SCHEMBL3089611 | 0.78 | HCAR2 (0.60) | SMN1; SMN2LMNAMAPTHTTKMT2A | |
| SCHEMBL1801877 | 0.78 | HCAR2 (0.60) | SMN1; SMN2LMNAMAPTHTTKMT2A | |
| SCHEMBL2464133 | 0.78 | MAPT (0.52) | SMN1; SMN2LMNAMAPTHTTKMT2A | |
| SCHEMBL12018827 | 0.78 | HCAR2 (0.60) | SMN1; SMN2LMNAMAPTHTTKMT2A | |
| SCHEMBL2464131 | 0.78 | MAPT (0.52) | SMN1; SMN2LMNAMAPTHTTKMT2A | |
| 2-Thiophenenecarboxaldehyde SCHEMBL7504082 | 0.78 | DPP4 (0.39) | SMN1; SMN2LMNAMAPTHTTKMT2A | |
| SCHEMBL31736350 | 0.76 | HCAR2 (0.58) | SMN1; SMN2LMNAMAPTHTTKMT2A | |
| SCHEMBL2460093 | 0.70 | RAB9A (0.39) | SMN1; SMN2LMNAMAPTHTTKMT2A | |
| SCHEMBL6550838 | 0.70 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNAMAPTHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110237633-A1 | SMALL MOLECULE MODULATORS OF HEPATOCYTE GROWTH FACTOR (SCATTER FACTOR) ACTIVITY | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2011-09-29 | — | — | US | disclosed |
| WO-2010068287-A2 | SMALL MOLECULE MODULATORS OF HEPATOCYTE GROWTH FACTOR (SCATTER FACTOR) ACTIVITY | ANGION BIOMEDICA CORP. (US) | 2010-06-17 | — | — | WO | disclosed |
| EP-0257573-B1 | Soluble electrically conductive polymers, method of producing them and their use | HOECHST AG (DE) | 1994-10-12 | — | — | EP | disclosed |
| US-5286414-A | Soluble oligomer of substituted thiophenes; non-conductive polymer; dipolar aprotic solvent; antistatic finish | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-02-15 | — | — | US | disclosed |
| EP-0292905-B1 | ELECTRICALLY CONDUCTIVE COATING COMPOSITION, METHOD FOR ITS MANUFACTURE AND ITS USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-10-06 | — | — | EP | disclosed |
| US-5093033-A | Coatings for nonconductive films and fibers | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-03-03 | — | — | US | disclosed |
| US-5066731-A | Process for modifying electroconductive polymers using ion exchange | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-11-19 | — | — | US | disclosed |
| EP-0239846-B1 | FLEXIBLE AND ELECTRICALLY CONDUCTING COMPOSITE MATERIALS, PROCESS FOR THEIR PREPARATION AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-11-14 | — | — | EP | disclosed |
| EP-0313998-A2 | Modified electrical conductive polymers | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-05-03 | — | — | EP | disclosed |
| EP-0292905-A2 | Electrically conductive coating composition, method for its manufacture and its use | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-11-30 | — | — | EP | disclosed |
| EP-0257573-A1 | Soluble electrically conductive polymers, method of producing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-03-02 | — | — | EP | disclosed |
| EP-0239846-A1 | Flexible and electrically conducting composite materials, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-10-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110237633-A1 | SMALL MOLECULE MODULATORS OF HEPATOCYTE GROWTH FACTOR (SCATTER FACTOR) ACTIVITY | HGF, HDGF, MET | SMN1; SMN2 3462/4885LMNA 4631/4885MAPT 3790/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.