Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 15/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 12/20 | 0.51 |
| ▸ | TMEM97 | Q5BJF2 | 6/20 | 0.51 |
| ▸ | DRD3 | P35462 | 3/20 | 0.47 |
| ▸ | DRD5 | P21918 | 1/20 | 0.45 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | PREP | P48147 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16600153 | 0.92 | DRD4 (0.55) | DRD4SIGMAR1TMEM97DRD3DRD5 | |
| SCHEMBL16600673 | 0.85 | LIPG (0.55) | LIPG | |
| SCHEMBL21638171 | 0.85 | LIPG (0.55) | LIPG | |
| SCHEMBL2459133 | 0.83 | MGLL (0.49) | DRD4SIGMAR1TMEM97LIPGFAAH | |
| SCHEMBL21723006 | 0.83 | CARM1 (0.49) | LIPGFAAHMGLL | |
| SCHEMBL5809457 | 0.83 | CARM1 (0.49) | LIPGFAAHMGLL | |
| SCHEMBL16614220 | 0.81 | DRD4 (0.53) | DRD4SIGMAR1TMEM97DRD3DRD5 | |
| SCHEMBL2526379 | 0.81 | GRIN2D (0.52) | SIGMAR1TMEM97LIPG | |
| SCHEMBL2525766 | 0.81 | GRIN2D (0.52) | SIGMAR1TMEM97LIPG | |
| SCHEMBL18426023 | 0.81 | GRIN2D (0.52) | SIGMAR1TMEM97LIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2367787-A1 | 3-PHENYL-3-METHOXYPYRROLIDINE DERIVATIVES AS MODULATORS OF CORTICAL CATECHOLAMINERGIC NEUROTRANSMISSION | NSAB, Filial af NeuroSearch Sweden AB, Sverige (DK) | 2011-09-28 | — | — | EP | disclosed |
| EP-2367788-A1 | 3-PHENYL-3-METHOXYPYRROLIDINE DERIVATIVES AS MODULATORS OF CORTICAL CATECHOLAMINERGIC NEUROTRANSMISSION | NSAB, Filial af NeuroSearch Sweden AB, Sverige (DK) | 2011-09-28 | — | — | EP | disclosed |