Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 13/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 12/20 | 0.55 |
| ▸ | TMEM97 | Q5BJF2 | 4/20 | 0.55 |
| ▸ | DRD3 | P35462 | 5/20 | 0.51 |
| ▸ | DRD5 | P21918 | 1/20 | 0.49 |
| ▸ | MGLL | Q99685 | 2/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.44 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.44 |
| ▸ | PREP | P48147 | 1/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.43 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2458433 | 0.92 | DRD4 (0.51) | DRD4SIGMAR1TMEM97DRD3DRD5 | |
| SCHEMBL16614220 | 0.86 | DRD4 (0.53) | DRD4SIGMAR1TMEM97DRD3DRD5 | |
| SCHEMBL4013732 | 0.85 | CARM1 (0.54) | MGLLFAAHGRIN2DGRIN3BGRIN1 | |
| SCHEMBL16614219 | 0.83 | DRD4 (0.53) | DRD4SIGMAR1TMEM97DRD3 | |
| SCHEMBL23365208 | 0.83 | CARM1 (0.58) | DRD4SIGMAR1TMEM97MGLLFAAH | |
| SCHEMBL31381316 | 0.81 | DRD4 (0.49) | DRD4SIGMAR1TMEM97DRD3DRD5 | |
| SCHEMBL21409412 | 0.79 | CARM1 (0.54) | SIGMAR1TMEM97GRIN2DGRIN3BGRIN1 | |
| SCHEMBL23365206 | 0.79 | CYP2C9 (0.52) | SIGMAR1FAAH | |
| SCHEMBL27629882 | 0.78 | CARM1 (0.57) | MGLLSCN9AGRM2GRM3GRIN2D | |
| SCHEMBL20569837 | 0.78 | MGLL (0.41) | DRD4SIGMAR1TMEM97DRD3MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3049405-A1 | AUTOTAXIN INHIBITOR COMPOUNDS | Pharmakea Inc. (US) | 2016-08-03 | — | — | EP | disclosed |
| US-20160214935-A1 | AUTOTAXIN INHIBITOR COMPOUNDS | DF 2024 IP ACQUISITION, LLC | 2016-07-28 | — | — | US | disclosed |
| WO-2015048301-A1 | AUTOTAXIN INHIBITOR COMPOUNDS | PHARMAKEA, INC. (US) | 2015-04-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160214935-A1 | AUTOTAXIN INHIBITOR COMPOUNDS | ENPP2, SERPINB1, SERPINE1 | DRD4 4856/4885SIGMAR1 4804/4885TMEM97 4569/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.