SCHEMBL16600673

SCHEMBL16600673

O=C(O)N1CCC(OCc2ccc(F)cc2)C1

nearest known ligand 0.55

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 1/20 0.55
CARM1 Q86X55 1/20 0.49
PRMT6 Q96LA8 1/20 0.49
BCHE P06276 2/20 0.47
NAAA Q02083 3/20 0.46
SLC18A3 Q16572 2/20 0.44
CNR1 P21554 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21638171 1.00 LIPG (0.55) LIPGCARM1PRMT6BCHENAAA
SCHEMBL4013732 0.92 CARM1 (0.54) LIPGCARM1PRMT6BCHENAAA
SCHEMBL16422780 0.88 NAAA (0.54) LIPGCARM1PRMT6BCHENAAA
SCHEMBL16600562 0.88 LIPG (0.51) LIPGCARM1PRMT6BCHENAAA
SCHEMBL18426023 0.87 GRIN2D (0.52) LIPGCARM1PRMT6BCHENAAA
SCHEMBL2526379 0.87 GRIN2D (0.52) LIPGCARM1PRMT6BCHENAAA
SCHEMBL2525766 0.87 GRIN2D (0.52) LIPGCARM1PRMT6BCHENAAA
SCHEMBL21723006 0.86 CARM1 (0.49) LIPGCARM1PRMT6BCHENAAA
SCHEMBL2459133 0.86 MGLL (0.49) LIPGCARM1PRMT6BCHE
SCHEMBL5809457 0.86 CARM1 (0.49) LIPGCARM1PRMT6BCHENAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110475775-B 4-pyridone compound or salt thereof, pharmaceutical composition containing 4-pyridone compound, and agent 富士胶片株式会社 2023-05-09 CN disclosed
US-11161830-B2 4-pyridone compound or salt thereof, and pharmaceutical composition and formulation including same FUJIFILM CORPORATION (JP) 2021-11-02 US disclosed
EP-3604301-B1 4-PYRIDONE COMPOUND OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION AND FORMULATION INCLUDING SAME FUJIFILM CORP (JP) 2021-09-22 EP disclosed
EP-3604301-A1 4-PYRIDONE COMPOUND OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION AND FORMULATION INCLUDING SAME FUJIFILM Corporation (JP) 2020-02-05 EP disclosed
US-9850203-B2 Autotaxin inhibitor compounds PHARMAKEA, INC. (US) 2017-12-26 US disclosed
EP-3049405-A1 AUTOTAXIN INHIBITOR COMPOUNDS Pharmakea Inc. (US) 2016-08-03 EP disclosed
US-20160214935-A1 AUTOTAXIN INHIBITOR COMPOUNDS DF 2024 IP ACQUISITION, LLC 2016-07-28 US disclosed
WO-2015048301-A1 AUTOTAXIN INHIBITOR COMPOUNDS PHARMAKEA, INC. (US) 2015-04-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11161830-B2 4-pyridone compound or salt thereof, and pharmaceutical composition and formulation including same HAVCR2, HBS1L, PHKB LIPG 4820/4885CARM1 2911/4885PRMT6 1138/4885
US-20160214935-A1 AUTOTAXIN INHIBITOR COMPOUNDS ENPP2, SERPINB1, SERPINE1 LIPG 1003/4885CARM1 4495/4885PRMT6 3359/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.