Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.61 |
| ▸ | CA2 | P00918 | 2/20 | 0.61 |
| ▸ | CA7 | P43166 | 2/20 | 0.61 |
| ▸ | CA9 | Q16790 | 2/20 | 0.61 |
| ▸ | CA12 | O43570 | 1/20 | 0.61 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.61 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | NOS3 | P29474 | 2/20 | 0.48 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.48 |
| ▸ | HTR3B | O95264 | 1/20 | 0.48 |
| ▸ | HTR3A | P46098 | 1/20 | 0.48 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.48 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL144129 | 0.97 | CA1 (0.65) | CA1CA2CA7CA9CA12 | |
| Hydrochloric Acid SCHEMBL4175940 | 0.94 | CA1 (0.61) | CA1CA2CA7CA9CA12 | |
| Iodide SCHEMBL10788331 | 0.94 | CA1 (0.61) | CA1CA2CA7CA9CA12 | |
| Bromide SCHEMBL8745388 | 0.94 | CA1 (0.61) | CA1CA2CA7CA9CA12 | |
| Fluoride Ion SCHEMBL244398 | 0.91 | CA4 (0.56) | CA1CA2CA7CA9CA12 | |
| SCHEMBL282301 | 0.87 | CA1 (0.52) | CA1CA2CA7CA9CA12 | |
| SCHEMBL13401281 | 0.87 | ACHE (0.71) | CA1CA2CA7CA9CA12 | |
| Bromide SCHEMBL10826980 | 0.87 | ESR2 (0.54) | CA1CA2CA7CA9CA12 | |
| SCHEMBL126675 | 0.87 | CA4 (0.59) | CA1CA2CA7CA9CA12 | |
| Fluoride SCHEMBL126455 | 0.87 | CA4 (0.52) | CA1CA2CA7CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3284736-B1 | FLUORINATION OF AROMATIC RING SYSTEMS | NUTECH VENTURES (US) | 2021-03-03 | — | — | EP | disclosed |
| EP-3284736-A1 | FLUORINATION OF AROMATIC RING SYSTEMS | NUtech Ventures (US) | 2018-02-21 | — | — | EP | disclosed |
| EP-2537826-B1 | Fluorination of aromatic ring systems | NUTECH VENTURES (US) | 2017-03-08 | — | — | EP | disclosed |
| US-9302990-B2 | Fluorination of aromatic ring systems | NUTECH VENTURES (US) | 2016-04-05 | — | — | US | disclosed |
| EP-2726446-A2 | FLUORINATION OF AROMATIC RING SYSTEMS | Nutech Ventures (US) | 2014-05-07 | — | — | EP | disclosed |
| US-8604213-B2 | Fluorination of aromatic ring systems | NUTECH VENTURES (US) | 2013-12-10 | — | — | US | disclosed |
| WO-2013003734-A2 | FLUORINATION OF AROMATIC RING SYSTEMS | NUTECH VENTURES (US) | 2013-01-03 | — | — | WO | disclosed |
| EP-2537826-A1 | Fluorination of aromatic ring systems | Nutech Ventures (US) | 2012-12-26 | — | — | EP | disclosed |
| US-20120004417-A1 | FLUORINATION OF AROMATIC RING SYSTEMS | NATIONAL SCIENCE FOUNDATION | 2012-01-05 | — | — | US | disclosed |
| US-20110313170-A1 | Fluorination of Aromatic Ring Systems | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 2011-12-22 | — | — | US | disclosed |
| EP-2349977-A2 | FLUORINATION OF AROMATIC RING SYSTEMS | The Board of Regents of the University of Nebraska (US) | 2011-08-03 | — | — | EP | disclosed |
| WO-2010048170-A2 | FLUORINATION OF AROMATIC RING SYSTEMS | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 2010-04-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120004417-A1 | FLUORINATION OF AROMATIC RING SYSTEMS | PFAS, SLC43A1, DDC | CA1 3898/4885CA2 3635/4885CA7 3073/4885 |
| US-20110313170-A1 | Fluorination of Aromatic Ring Systems | PFAS, SLC43A1, DDC | CA1 3898/4885CA2 3635/4885CA7 3073/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.