Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC1 | P19801 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.33 |
| ▸ | MELK | Q14680 | 1/20 | 0.31 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.31 |
| ▸ | TLK2 | Q86UE8 | 1/20 | 0.31 |
| ▸ | NEK7 | Q8TDX7 | 1/20 | 0.31 |
| ▸ | NEK6 | Q9HC98 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2458564 | 1.00 | AOC1 (0.43) | AOC1KDM4EBLMNPSR1CYP3A4 | |
| SCHEMBL2458794 | 0.72 | AOC1 (0.43) | AOC1KDM4EBLMNPSR1CYP3A4 | |
| SCHEMBL2458792 | 0.72 | AOC1 (0.43) | AOC1KDM4EBLMNPSR1CYP3A4 | |
| SCHEMBL2460060 | 0.69 | AOC1 (0.43) | AOC1KDM4EBLMNPSR1CYP3A4 | |
| SCHEMBL2458376 | 0.69 | AOC1 (0.43) | AOC1KDM4EBLMNPSR1CYP3A4 | |
| SCHEMBL2458600 | 0.67 | AOC1 (0.44) | AOC1KDM4EBLMNPSR1CYP3A4 | |
| SCHEMBL2458268 | 0.67 | AOC1 (0.44) | AOC1KDM4EBLMNPSR1CYP3A4 | |
| SCHEMBL2458597 | 0.67 | AOC1 (0.44) | AOC1KDM4EBLMNPSR1CYP3A4 | |
| SCHEMBL2458266 | 0.67 | AOC1 (0.44) | AOC1KDM4EBLMNPSR1CYP3A4 | |
| SCHEMBL2465545 | 0.66 | AOC1 (0.43) | AOC1KDM4EBLMNPSR1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110237633-A1 | SMALL MOLECULE MODULATORS OF HEPATOCYTE GROWTH FACTOR (SCATTER FACTOR) ACTIVITY | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2011-09-29 | — | — | US | disclosed |
| WO-2010068287-A2 | SMALL MOLECULE MODULATORS OF HEPATOCYTE GROWTH FACTOR (SCATTER FACTOR) ACTIVITY | ANGION BIOMEDICA CORP. (US) | 2010-06-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110237633-A1 | SMALL MOLECULE MODULATORS OF HEPATOCYTE GROWTH FACTOR (SCATTER FACTOR) ACTIVITY | HGF, HDGF, MET | AOC1 3885/4885KDM4E 4565/4885BLM 3519/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.