Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 14/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 14/20 | 0.46 |
| ▸ | ATR | Q13535 | 8/20 | 0.45 |
| ▸ | ATRIP | Q8WXE1 | 7/20 | 0.45 |
| ▸ | CHEK1 | O14757 | 6/20 | 0.45 |
| ▸ | PIK3C3 | Q8NEB9 | 5/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23103865 | 0.72 | PIK3C3 (0.46) | ATRATRIPPIK3C3 | |
| SCHEMBL24587271 | 0.71 | CHRNB2 (0.42) | — | |
| SCHEMBL24156133 | 0.70 | PDCD1 (0.49) | PDCD1CD274ATRATRIPCHEK1 | |
| SCHEMBL27132327 | 0.70 | PDCD1 (0.49) | PDCD1CD274ATRATRIPCHEK1 | |
| SCHEMBL24156413 | 0.70 | PDCD1 (0.49) | PDCD1CD274ATRATRIPCHEK1 | |
| SCHEMBL31247633 | 0.70 | TYK2 (0.54) | PDCD1CD274ATRPIK3C3 | |
| SCHEMBL21459330 | 0.69 | GABRA1 (0.41) | PDCD1CD274ATRATRIPCHEK1 | |
| SCHEMBL31303264 | 0.69 | GABRA1 (0.41) | PDCD1CD274ATRATRIPCHEK1 | |
| SCHEMBL21459329 | 0.69 | GABRA1 (0.41) | PDCD1CD274ATRATRIPCHEK1 | |
| SCHEMBL18892003 | 0.69 | MAPK1 (0.50) | ATRPIK3C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022135430-A1 | HETEROARYL COMPOUNDS, PREPARATION METHODS AND USES THEREOF | InventisBio Co., Ltd. (CN) | 2022-06-30 | — | — | WO | disclosed |