Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 3/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 5/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GLP1R | P43220 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24587389 | 0.80 | NR1H2 (0.37) | CHRNB2CHRNA4NR1H2NR1H3PDE10A | |
| SCHEMBL24587383 | 0.80 | NR1H2 (0.39) | CHRNB2CHRNA4NR1H2NR1H3 | |
| SCHEMBL19145095 | 0.75 | CHRNB2 (0.51) | CHRNB2CHRNA4KDM4E | |
| SCHEMBL28602649 | 0.74 | GPR119 (0.39) | CHRNB2CHRNA4METGPR119KDM4E | |
| SCHEMBL24587384 | 0.71 | PDCD1 (0.46) | — | |
| SCHEMBL30811705 | 0.69 | CHRNB2 (0.49) | CHRNB2CHRNA4KDM4E | |
| SCHEMBL10178824 | 0.68 | NPC1 (0.43) | KDM4EMEN1KMT2A | |
| SCHEMBL10178237 | 0.68 | PTGS2 (0.41) | MEN1KMT2A | |
| SCHEMBL24587270 | 0.68 | AGBL2 (0.36) | NR1H2KDM4E | |
| SCHEMBL20389083 | 0.68 | CHRNB2 (0.38) | CHRNB2CHRNA4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022135430-A1 | HETEROARYL COMPOUNDS, PREPARATION METHODS AND USES THEREOF | InventisBio Co., Ltd. (CN) | 2022-06-30 | — | — | WO | disclosed |