SCHEMBL8992948

SCHEMBL8992948

Nc1cccc(C(=O)c2cc(N)cc(N)c2)c1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PBRM1 Q86U86 1/20 0.77
NPC1 O15118 1/20 0.65
MITF O75030 1/20 0.65
LMNA P02545 1/20 0.65
POLB P06746 1/20 0.65
CA1 P00915 2/20 0.56
CA2 P00918 2/20 0.56
CA9 Q16790 2/20 0.56
CYP3A4 P08684 1/20 0.52
CASP1 P29466 1/20 0.52
RECQL P46063 1/20 0.52
TDP1 Q9NUW8 2/20 0.52
ATM Q13315 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
F2 P00734 1/20 0.50
PLG P00747 1/20 0.50
PRSS1 P07477 1/20 0.50
PRSS2 P07478 1/20 0.50
PRSS3 P35030 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29363032 0.93 PBRM1 (0.87) PBRM1NPC1MITFLMNAPOLB
SCHEMBL125621 0.93 PBRM1 (0.87) PBRM1NPC1MITFLMNAPOLB
SCHEMBL9282073 0.93 PBRM1 (0.87) PBRM1NPC1MITFLMNAPOLB
SCHEMBL9101086 0.91 PBRM1 (0.83) PBRM1NPC1MITFLMNAPOLB
SCHEMBL204263 0.91 PBRM1 (0.83) PBRM1NPC1MITFLMNAPOLB
Hydrochloric Acid SCHEMBL8643223 0.91 PBRM1 (0.83) PBRM1NPC1MITFLMNAPOLB
SCHEMBL29492479 0.91 PBRM1 (0.83) PBRM1NPC1MITFLMNAPOLB
Hydrochloric Acid SCHEMBL8962669 0.89 PBRM1 (0.80) PBRM1NPC1MITFLMNAPOLB
SCHEMBL203373 0.89 PBRM1 (0.88) PBRM1NPC1MITFLMNAPOLB
SCHEMBL29492473 0.89 PBRM1 (0.88) PBRM1NPC1MITFLMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260035513-A1 RESIN COMPOSITION, REINFORCED COMPOSITE MATERIAL, SHAPED PRODUCT, AND METHOD OF RECOVERING REINFORCING FIBER FROM REINFORCED COMPOSITE MATERIAL ASAHI KASEI KABUSHIKI KAISHA (JP) 2026-02-05 US disclosed
EP-4578892-A1 RESIN COMPOSITION, COMPOSITE REINFORCING MATERIAL, MOLDED BODY, AND METHOD FOR RECOVERING REINFORCING FIBERS FROM COMPOSITE REINFORCING MATERIAL Asahi Kasei Kabushiki Kaisha (JP) 2025-07-02 EP disclosed
WO-2024043285-A1 RESIN COMPOSITION, COMPOSITE REINFORCING MATERIAL, MOLDED BODY, AND METHOD FOR RECOVERING REINFORCING FIBERS FROM COMPOSITE REINFORCING MATERIAL 旭化成株式会社 2024-02-29 WO disclosed
EP-0450926-B1 Fluorine-containing polyimides and precursors thereof HITACHI CHEMICAL CO LTD (JP) 1996-07-31 EP disclosed
US-5401878-A Fluorinated unsaturated alkyl ether aryldiamines for polyimide polymers with heat resistance and waterproofing HITACHI CHEMICAL COMPANY, LTD. (JP) 1995-03-28 US disclosed
US-5270438-A Fluorine-containing polyimides and precursors thereof HITACHI CHEMICAL COMPANY, LTD. (JP) 1993-12-14 US disclosed
EP-0450926-A2 Fluorine-containing polyimides and precursors thereof Hitachi Chemical Co., Ltd. (JP) 1991-10-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260035513-A1 RESIN COMPOSITION, REINFORCED COMPOSITE MATERIAL, SHAPED PRODUCT, AND METHOD OF RECOVERING REINFORCING FIBER FROM REINFORCED COMPOSITE MATERIAL TAF1, TAF1L, TAF9 PBRM1 1239/4885NPC1 4475/4885MITF 1633/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.