Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.48 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.48 |
| ▸ | SOD1 | P00441 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | PPARD | Q03181 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | ESRRB | O95718 | 1/20 | 0.41 |
| ▸ | ESRRG | P62508 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29754911 | 0.81 | KMT2A (0.53) | FFAR1KDM4EHTTALDH1A1GAA | |
| SCHEMBL27090181 | 0.81 | KMT2A (0.53) | FFAR1KDM4EHTTALDH1A1GAA | |
| SCHEMBL29754989 | 0.78 | FFAR1 (0.64) | FFAR1MAPTLMNAHTTALDH1A1 | |
| SCHEMBL27090197 | 0.78 | FFAR1 (0.64) | FFAR1MAPTLMNAHTTALDH1A1 | |
| SCHEMBL30831879 | 0.77 | SMN1; SMN2 (0.65) | NR4A1NR4A2NR4A3SOD1FFAR1 | |
| SCHEMBL1986392 | 0.77 | SMN1; SMN2 (0.65) | NR4A1NR4A2NR4A3SOD1FFAR1 | |
| SCHEMBL18120698 | 0.77 | SOD1 (0.51) | NR4A1NR4A2NR4A3SOD1FFAR1 | |
| SCHEMBL14065575 | 0.76 | KDM4E (0.51) | NR4A1NR4A2NR4A3SOD1FFAR1 | |
| SCHEMBL12993061 | 0.75 | ALDH1A1 (0.51) | SOD1FFAR1KDM4ELMNAALDH1A1 | |
| SCHEMBL28163129 | 0.74 | ESRRG (0.44) | NR4A1NR4A2NR4A3SOD1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022135617-A1 | NOVEL NAMPT ENZYME AGONIST AND PREPARATION AND USE THEREOF | 清华大学 | 2022-06-30 | — | — | WO | disclosed |