Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 8/20 | 0.38 |
| ▸ | RAB9A | P51151 | 8/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPN | P05981 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 3/20 | 0.37 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.36 |
| ▸ | STS | P08842 | 3/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21116161 | 0.85 | NPC1 (0.39) | KDM4EALDH1A1HPGDGAANPC1 | |
| SCHEMBL27105756 | 0.84 | RXFP1 (0.41) | KDM4EALDH1A1HPGDGAANPC1 | |
| SCHEMBL24595646 | 0.80 | RXFP1 (0.42) | KDM4EALDH1A1HPGDGAANPC1 | |
| SCHEMBL21116032 | 0.78 | THRB (0.38) | KDM4EALDH1A1HPGDGAANPC1 | |
| SCHEMBL18535528 | 0.78 | KDM4E (0.48) | KDM4EALDH1A1HPGDGAANPC1 | |
| SCHEMBL18535532 | 0.73 | NPC1 (0.38) | KDM4EALDH1A1HPGDGAANPC1 | |
| SCHEMBL18535661 | 0.73 | RAB9A (0.41) | KDM4EALDH1A1HPGDGAANPC1 | |
| SCHEMBL24595655 | 0.72 | NPC1 (0.38) | KDM4EALDH1A1HPGDGAANPC1 | |
| SCHEMBL23713569 | 0.72 | STS (0.46) | KDM4EALDH1A1HPGDGAANPC1 | |
| SCHEMBL24595649 | 0.72 | THRB (0.39) | KDM4EALDH1A1HPGDGAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3502147-A1 | COMPOSITION FOR OPHTHALMOLOGICAL PRODUCTS | Merck Patent GmbH (DE) | 2019-06-26 | — | — | EP | disclosed |