Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | STAT5B | P51692 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24596346 | 0.80 | NPSR1 (0.38) | NPSR1ALDH1A1HSD17B10MAPTMAPK1 | |
| SCHEMBL24596265 | 0.75 | NPSR1 (0.39) | STAT5BNPSR1ALDH1A1MAPTKDM4E | |
| SCHEMBL19737998 | 0.73 | NPSR1 (0.43) | NPSR1ALDH1A1MAPTMAPK1KDM4E | |
| SCHEMBL27338562 | 0.71 | ALDH1A1 (0.34) | ADORA2AADORA2BADORA1STAT5BALDH1A1 | |
| SCHEMBL21879900 | 0.70 | NPSR1 (0.41) | NPSR1ALDH1A1MAPTMAPK1KDM4E | |
| SCHEMBL9386264 | 0.70 | KDM4E (0.43) | ALDH1A1HSD17B10MAPTKDM4ELMNA | |
| SCHEMBL24548461 | 0.69 | ADORA2A (0.39) | ADORA2AADORA2BADORA1ALDH1A1HSD17B10 | |
| SCHEMBL29789969 | 0.69 | NPSR1 (0.39) | NPSR1ALDH1A1MAPTMAPK1KDM4E | |
| SCHEMBL31134762 | 0.66 | NPSR1 (0.39) | STAT5BNPSR1ALDH1A1HSD17B10MAPT | |
| SCHEMBL289465 | 0.65 | CYP4F2 (0.40) | NPSR1ALDH1A1HSD17B10MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022143864-A1 | TRICYCLIC COMPOUND AND USE THEREOF | 江苏先声药业有限公司 | 2022-07-07 | — | — | WO | disclosed |