Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14966301 | 0.72 | KDM4E (0.43) | KDM4EALDH1A1LMNAKMT2AHSD17B10 | |
| SCHEMBL21394881 | 0.71 | LMNA (0.47) | KDM4EALDH1A1LMNAKMT2AHSD17B10 | |
| SCHEMBL24596235 | 0.70 | ADORA2A (0.35) | KDM4EALDH1A1LMNAHSD17B10TSHR | |
| SCHEMBL15971030 | 0.68 | ALDH1A1 (0.43) | KDM4EALDH1A1KMT2AHSD17B10TSHR | |
| SCHEMBL22939299 | 0.68 | CA12 (0.43) | KDM4EFGFR1ALDH1A1LMNAKMT2A | |
| SCHEMBL15660917 | 0.68 | KDM4E (0.53) | KDM4EFGFR1ALDH1A1LMNAKMT2A | |
| SCHEMBL23467051 | 0.68 | KDM4E (0.47) | KDM4EFGFR1ALDH1A1LMNAKMT2A | |
| SCHEMBL15687493 | 0.68 | KDM4E (0.44) | KDM4EFGFR1ALDH1A1LMNAKMT2A | |
| SCHEMBL11679816 | 0.66 | FGFR1 (0.60) | KDM4EFGFR1ALDH1A1LMNAKMT2A | |
| SCHEMBL15970936 | 0.66 | MEN1 (0.44) | KDM4EALDH1A1KMT2AHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0621276-A1 | Angiotensin II receptor blocking 2,3,6-substituted quinazolinones | AMERICAN CYANAMID COMPANY (US) | 1994-10-26 | — | — | EP | disclosed |