SCHEMBL24596459

SCHEMBL24596459

c1ccc(-n2c3ccccc3c3cc(-c4ccc5c(c4)c4ccccc4n5-c4nc(-c5ccc6c(c5)sc5ccccc56)c5ccccc5n4)ccc32)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.38
KDM4E B2RXH2 4/20 0.38
ATM Q13315 2/20 0.38
HPGD P15428 5/20 0.36
ALDH1A1 P00352 4/20 0.36
MAPT P10636 2/20 0.36
NPSR1 Q6W5P4 1/20 0.36
PTGER4 P35408 1/20 0.35
LMNA P02545 3/20 0.34
MAPK1 P28482 2/20 0.33
POLB P06746 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
HTT P42858 1/20 0.33
RAB9A P51151 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
HSD17B10 Q99714 2/20 0.31
NPC1 O15118 1/20 0.31
TP53 P04637 1/20 0.31
NPY5R Q15761 1/20 0.30
PDE1B Q01064 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15682527 0.96 HPGD (0.38) L3MBTL1KDM4EATMHPGDALDH1A1
SCHEMBL19769846 0.95 L3MBTL1 (0.38) L3MBTL1KDM4EATMHPGDALDH1A1
SCHEMBL24596498 0.95 L3MBTL1 (0.38) L3MBTL1KDM4EATMHPGDALDH1A1
SCHEMBL15034647 0.94 HPGD (0.37) L3MBTL1KDM4EATMHPGDALDH1A1
SCHEMBL24801508 0.93 L3MBTL1 (0.35) L3MBTL1KDM4EATMHPGDALDH1A1
SCHEMBL24596518 0.93 HPGD (0.36) L3MBTL1KDM4EATMHPGDALDH1A1
SCHEMBL15682482 0.93 ALDH1A1 (0.43) L3MBTL1KDM4EATMHPGDALDH1A1
SCHEMBL15682506 0.92 ALDH1A1 (0.42) L3MBTL1KDM4EATMHPGDALDH1A1
SCHEMBL8817922 0.91 ALDH1A1 (0.39) L3MBTL1KDM4EATMHPGDALDH1A1
SCHEMBL8817943 0.91 ALDH1A1 (0.39) L3MBTL1KDM4EATMHPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220216433-A1 ELECTROLUMINESCENT DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2022-07-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220216433-A1 ELECTROLUMINESCENT DEVICE EML4, EMC2, L1CAM L3MBTL1 2089/4885KDM4E 1502/4885ATM 2121/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.