Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PNP | P00491 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12826793 | 0.88 | PDE4D (0.55) | LMNATP53PNPHTTPDE4D | |
| SCHEMBL19003221 | 0.84 | PDE4A (0.43) | LMNATP53ALDH1A1PDE4DP2RX7 | |
| SCHEMBL14276903 | 0.80 | LMNA (0.48) | LMNATP53ALDH1A1MAPTTDP1 | |
| SCHEMBL23585882 | 0.79 | LMNA (0.57) | LMNATP53ALDH1A1TDP1PNP | |
| SCHEMBL11959962 | 0.77 | LMNA (0.61) | LMNATP53ALDH1A1MAPTTDP1 | |
| SCHEMBL26030330 | 0.77 | LMNA (0.61) | LMNATP53ALDH1A1MAPTTDP1 | |
| SCHEMBL15713278 | 0.74 | NT5E (0.49) | LMNATP53ALDH1A1MAPTTDP1 | |
| SCHEMBL23585953 | 0.74 | NT5E (0.50) | LMNATP53ALDH1A1MAPTTDP1 | |
| SCHEMBL4151824 | 0.73 | YTHDC1 (0.66) | LMNATP53ALDH1A1PNPHTT | |
| SCHEMBL30332447 | 0.72 | LMNA (0.50) | LMNATP53ALDH1A1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4273153-A1 | ADENOSINE A3 RECEPTOR AGONISTS, PREPARATION METHODS AND USES THEREOF | Zhejiang Vimgreen Pharmaceuticals, Ltd (CN) | 2023-11-08 | — | — | EP | disclosed |
| WO-2022143740-A1 | ADENOSINE A3 RECEPTOR AGONIST, PREPARATION METHOD THEREFOR, AND USE THEREOF | 浙江春禾医药科技有限公司 | 2022-07-07 | — | — | WO | disclosed |