Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 15/20 | 0.78 |
| ▸ | ADORA1 | P30542 | 7/20 | 0.70 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.70 |
| ▸ | TP53 | P04637 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.64 |
| ▸ | HTR2C | P28335 | 1/20 | 0.62 |
| ▸ | PPARG | P37231 | 1/20 | 0.62 |
| ▸ | HTR2B | P41595 | 1/20 | 0.62 |
| ▸ | PPARD | Q03181 | 1/20 | 0.62 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24600767 | 0.92 | ADORA3 (0.65) | ADORA3ADORA1ADORA2ATP53MAPT | |
| SCHEMBL24601162 | 0.91 | ALDH1A1 (0.70) | ADORA3ADORA1ADORA2ATP53MAPT | |
| SCHEMBL7743869 | 0.88 | ADORA3 (0.66) | ADORA3ADORA1ADORA2ATP53MAPT | |
| SCHEMBL1120610 | 0.85 | ACHE (0.65) | ADORA3ADORA1ADORA2ATP53MAPT | |
| SCHEMBL1120608 | 0.85 | ACHE (0.65) | ADORA3ADORA1ADORA2ATP53MAPT | |
| SCHEMBL1120612 | 0.85 | ACHE (0.65) | ADORA3ADORA1ADORA2ATP53MAPT | |
| SCHEMBL4803791 | 0.84 | ALDH1A1 (0.61) | ADORA3ADORA1ADORA2ATP53MAPT | |
| SCHEMBL4803780 | 0.84 | ALDH1A1 (0.61) | ADORA3ADORA1ADORA2ATP53MAPT | |
| SCHEMBL4803787 | 0.84 | ALDH1A1 (0.61) | ADORA3ADORA1ADORA2ATP53MAPT | |
| SCHEMBL24078860 | 0.83 | ACHE (0.66) | ADORA3ADORA1ADORA2ATP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4273153-A1 | ADENOSINE A3 RECEPTOR AGONISTS, PREPARATION METHODS AND USES THEREOF | Zhejiang Vimgreen Pharmaceuticals, Ltd (CN) | 2023-11-08 | — | — | EP | disclosed |
| WO-2022143740-A1 | ADENOSINE A3 RECEPTOR AGONIST, PREPARATION METHOD THEREFOR, AND USE THEREOF | 浙江春禾医药科技有限公司 | 2022-07-07 | — | — | WO | disclosed |