Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | FAAH | O00519 | 1/20 | 0.51 |
| ▸ | MGLL | Q99685 | 1/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.49 |
| ▸ | COMT | P21964 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | APLNR | P35414 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
| ▸ | TACR2 | P21452 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24601360 | 0.95 | HPGD (0.56) | ALDH1A1KDM4EHSD17B10CYP1A2HPGD | |
| SCHEMBL18820385 | 0.89 | KDM4E (0.59) | ALDH1A1KDM4EHSD17B10CYP1A2HPGD | |
| SCHEMBL10059356 | 0.82 | KDM4E (0.62) | ALDH1A1KDM4EHSD17B10CYP1A2HPGD | |
| SCHEMBL356681 | 0.80 | ALDH1A1 (0.80) | ALDH1A1KDM4EHSD17B10CYP1A2HPGD | |
| SCHEMBL22039469 | 0.78 | MAPK14 (0.49) | ALDH1A1KDM4EHSD17B10CYP1A2HPGD | |
| SCHEMBL3970272 | 0.78 | ALDH1A1 (0.77) | ALDH1A1KDM4EHSD17B10CYP1A2HPGD | |
| SCHEMBL16541555 | 0.78 | KDM4E (0.61) | ALDH1A1KDM4EHSD17B10CYP1A2HPGD | |
| SCHEMBL10059326 | 0.78 | KDM4E (0.61) | ALDH1A1KDM4EHSD17B10CYP1A2HPGD | |
| SCHEMBL24601361 | 0.76 | KDM4E (0.48) | ALDH1A1KDM4EHSD17B10CYP1A2HPGD | |
| SCHEMBL10059449 | 0.75 | BLM (0.57) | ALDH1A1KDM4EHSD17B10CYP1A2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022146980-A1 | COMPOSITIONS AND METHODS FOR INHIBITING FIBROSIS, INFLAMMATION AND CANCER | GEORGIA TECH RESEARCH CORPORATION (US) | 2022-07-07 | — | — | WO | disclosed |