Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.50 |
| ▸ | COMT | P21964 | 1/20 | 0.49 |
| ▸ | APLNR | P35414 | 2/20 | 0.45 |
| ▸ | MGLL | Q99685 | 2/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24601359 | 0.95 | ALDH1A1 (0.54) | HPGDALDH1A1HSD17B10KDM4ECYP1A2 | |
| SCHEMBL18820385 | 0.90 | KDM4E (0.59) | HPGDALDH1A1HSD17B10KDM4ECYP1A2 | |
| SCHEMBL10059356 | 0.83 | KDM4E (0.62) | HPGDALDH1A1HSD17B10KDM4ECYP1A2 | |
| SCHEMBL356681 | 0.81 | ALDH1A1 (0.80) | HPGDALDH1A1HSD17B10KDM4ECYP1A2 | |
| SCHEMBL22039469 | 0.79 | MAPK14 (0.49) | HPGDALDH1A1HSD17B10KDM4ECYP1A2 | |
| SCHEMBL10059326 | 0.79 | KDM4E (0.61) | HPGDALDH1A1HSD17B10KDM4ECYP1A2 | |
| SCHEMBL16541555 | 0.79 | KDM4E (0.61) | HPGDALDH1A1HSD17B10KDM4ECYP1A2 | |
| SCHEMBL10059449 | 0.76 | BLM (0.57) | HPGDALDH1A1HSD17B10KDM4ECYP1A2 | |
| SCHEMBL10059369 | 0.76 | ALDH1A1 (0.57) | HPGDALDH1A1HSD17B10KDM4ECYP1A2 | |
| SCHEMBL24601361 | 0.75 | KDM4E (0.48) | HPGDALDH1A1HSD17B10KDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022146980-A1 | COMPOSITIONS AND METHODS FOR INHIBITING FIBROSIS, INFLAMMATION AND CANCER | GEORGIA TECH RESEARCH CORPORATION (US) | 2022-07-07 | — | — | WO | disclosed |