Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.39 |
| ▸ | APLNR | P35414 | 2/20 | 0.37 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5886550 | 0.76 | KCNH2 (0.59) | KDM4EALDH1A1HPGDHSD17B10FFAR1 | |
| SCHEMBL24601359 | 0.76 | ALDH1A1 (0.54) | KDM4EALDH1A1HPGDHSD17B10CYP1A2 | |
| SCHEMBL19450251 | 0.76 | MAPK14 (0.75) | KDM4EALDH1A1HPGDHSD17B10CYP1A2 | |
| SCHEMBL24601360 | 0.75 | HPGD (0.56) | KDM4EALDH1A1HPGDHSD17B10CYP1A2 | |
| SCHEMBL28739809 | 0.73 | KCNH2 (0.54) | ALDH1A1FFAR1FFAR4MMP2MMP12 | |
| SCHEMBL5886652 | 0.73 | FFAR1 (0.63) | FFAR1FFAR4MMP2MMP12KCNH2 | |
| SCHEMBL3970272 | 0.73 | ALDH1A1 (0.77) | KDM4EALDH1A1HPGDHSD17B10CYP1A2 | |
| SCHEMBL5886588 | 0.69 | FFAR1 (0.53) | FFAR1FFAR4MMP2MMP12KCNH2 | |
| SCHEMBL8846653 | 0.67 | FFAR1 (0.51) | FFAR1FFAR4MMP2MMP12KCNH2 | |
| SCHEMBL3975362 | 0.67 | ALDH1A1 (0.67) | KDM4EALDH1A1HPGDHSD17B10CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022146980-A1 | COMPOSITIONS AND METHODS FOR INHIBITING FIBROSIS, INFLAMMATION AND CANCER | GEORGIA TECH RESEARCH CORPORATION (US) | 2022-07-07 | — | — | WO | disclosed |