SCHEMBL24601438

SCHEMBL24601438

Cc1cccc(C)c1-c1cccc2c3c4c5ccccc5n5c6c(-c7c(C)cccc7C)cccc6c(c6c7ccccc7n(c12)c63)c45

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALKBH5 Q6P6C2 1/20 0.41
FTO Q9C0B1 1/20 0.41
NTRK1 P04629 1/20 0.40
MAPT P10636 3/20 0.40
KDM4E B2RXH2 1/20 0.40
ALDH1A1 P00352 2/20 0.37
RAB9A P51151 2/20 0.37
LMNA P02545 1/20 0.37
PKM P14618 1/20 0.37
IDO1 P14902 1/20 0.37
MAPK1 P28482 1/20 0.37
MDM2 Q00987 1/20 0.37
MCL1 Q07820 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
MYC P01106 1/20 0.37
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
GAA P10253 1/20 0.35
CHEK1 O14757 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24601528 0.81 NTRK1 (0.39) ALKBH5FTONTRK1MAPTKDM4E
SCHEMBL24601445 0.81 HSD17B10 (0.34) MAPTKDM4EALDH1A1MCL1TDP1
SCHEMBL24601439 0.80 KIF11 (0.33) MAPTKDM4EALDH1A1TDP1
SCHEMBL24601481 0.80 NTRK1 (0.39) ALKBH5FTONTRK1MAPTKDM4E
SCHEMBL21718240 0.78 ALKBH5 (0.41) ALKBH5FTONTRK1MAPTKDM4E
SCHEMBL24601535 0.77 CYP1A2 (0.40) MAPTKDM4EALDH1A1LMNAMEN1
SCHEMBL22178472 0.76 MAPT (0.49) ALKBH5FTOMAPTKDM4EALDH1A1
SCHEMBL24601592 0.76 CYP1A2 (0.38) ALKBH5FTONTRK1MAPTKDM4E
SCHEMBL20857888 0.76 MAPT (0.37) ALKBH5FTONTRK1MAPTKDM4E
SCHEMBL24601434 0.75 PRKDC (0.35) MAPTKDM4EALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220213113-A1 NITROGEN-CONTAINING CONDENSED CYCLIC COMPOUNDS, FLUORESCENCE EMITTERS, ORGANIC ELECTROLUMINESCENT DEVICES, AND MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES SAMSUNG ELECTRONICS CO., LTD. (KR) 2022-07-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220213113-A1 NITROGEN-CONTAINING CONDENSED CYCLIC COMPOUNDS, FLUORESCENCE EMITTERS, ORGANIC ELECTROLUMINESCENT DEVICES, AND MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES NCL, NOC2L, NOLC1 ALKBH5 580/4885FTO 1886/4885NTRK1 3178/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.