SCHEMBL24601848

CC(C)C[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN=[N+]=[N-])NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)COCCOCCOCCNC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CCC(=O)O)C(N)=O

nearest known ligand 0.52

Predicted protein targets (top 12)

	gene	UniProt	supporting neighbours	confidence
▸	APLNR	P35414	1/20	0.52

▸	F2	P00734	1/20	0.46

▸	PLG	P00747	1/20	0.46

▸	PRSS1	P07477	1/20	0.46

▸	PRSS2	P07478	1/20	0.46

▸	PRSS3	P35030	1/20	0.46

▸	TPSAB1	Q15661	1/20	0.46

▸	KDM1A	O60341	1/20	0.45

▸	MAOB	P27338	1/20	0.45

▸	KDM5A	P29375	1/20	0.45

▸	KDM1B	Q8NB78	1/20	0.45

▸	CXCR4	P61073	4/20	0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL26004079	0.94	APLNR (0.57)	APLNRF2PLGPRSS1PRSS2
SCHEMBL22423719	0.80	RAMP3 (0.56)	KDM1AMAOBKDM5AKDM1B
Biotin SCHEMBL6521802	0.77	GLP1R (0.59)	APLNR
SCHEMBL30439761	0.76	PIN1 (0.51)	APLNR
SCHEMBL6176075	0.75	RAMP3 (0.52)	APLNR
SCHEMBL30439872	0.75	C5AR1 (0.60)	F2
SCHEMBL30439960	0.75	C5AR1 (0.57)	—
SCHEMBL10066224	0.75	RAMP3 (0.51)	F2PLGPRSS1PRSS2PRSS3
SCHEMBL30439594	0.74	CTSL (0.65)	CXCR4
SCHEMBL22550646	0.74	RAMP3 (0.53)	KDM1AMAOBKDM5AKDM1BCXCR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-11766414-B2	Compositions, delivery systems, and methods useful in tumor therapy	INDI MOLECULAR, INC. (US)	2023-09-26	—	—	US	disclosed
US-20220211648-A1	COMPOSITIONS, DELIVERY SYSTEMS, AND METHODS USEFUL IN TUMOR THERAPY	INDI MOLECULAR, INC.	2022-07-07	—	—	US	disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

Patent	Title	Text reads most about	Predicted target · text-rank
US-11766414-B2	Compositions, delivery systems, and methods useful in tumor therapy	TP53, BAX, RNASE1	APLNR 480/4885F2 462/4885PLG 65/4885
US-20220211648-A1	COMPOSITIONS, DELIVERY SYSTEMS, AND METHODS USEFUL IN TUMOR THERAPY	TP53, BAX, RNASE1	APLNR 480/4885F2 462/4885PLG 65/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.