Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 5/20 | 0.32 |
| ▸ | SAT1 | P21673 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25915063 | 0.95 | CYP2C19 (0.40) | CYP2C19MEN1KMT2AGLACYP1A2 | |
| SCHEMBL24673637 | 0.93 | CYP2C19 (0.39) | CYP2C19MEN1KMT2AGLACYP1A2 | |
| SCHEMBL25509805 | 0.89 | CHRNB2 (0.32) | CYP2C19MEN1KMT2AGLACYP1A2 | |
| SCHEMBL25828428 | 0.87 | SAT1 (0.36) | CYP2C19MEN1KMT2AGLACYP1A2 | |
| SCHEMBL22151226 | 0.81 | KISS1R (0.38) | PAOXHDAC6 | |
| SCHEMBL22149947 | 0.80 | ADH1B (0.41) | MEN1KMT2APAOXHDAC6KDM4E | |
| SCHEMBL23568550 | 0.80 | TSHR (0.37) | MEN1KMT2ATSHRPAOXALDH1A1 | |
| SCHEMBL22849280 | 0.80 | MEN1 (0.35) | MEN1KMT2A | |
| SCHEMBL26018156 | 0.79 | ALDH1A1 (0.45) | TSHRPAOXALDH1A1DNM1 | |
| SCHEMBL1834013 | 0.79 | PAOX (0.43) | CYP2C19MEN1KMT2AGLACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022147465-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2022-07-07 | — | — | WO | disclosed |