SCHEMBL2460912

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2461255	0.96	POLB (0.44)	RXFP1GAATDP1KDM4EALDH1A1
	SCHEMBL2579066	0.85	POLB (0.44)	RXFP1GAATDP1KDM4EALDH1A1
	SCHEMBL2460946	0.84	POLB (0.43)	RXFP1ACHEGAATDP1KDM4E
	SCHEMBL2578644	0.84	ESR1 (0.42)	RXFP1GAAKDM4EALDH1A1POLB
	SCHEMBL7909989	0.83	ESR1 (0.39)	ACHE
	SCHEMBL12175863	0.83	POLB (0.45)	RXFP1TDP1KDM4EALDH1A1LMNA
	Hydrochloric Acid SCHEMBL2578962	0.82	ESR1 (0.38)	ACHE
	SCHEMBL7910678	0.82	RAB9A (0.40)	RXFP1GAAALDH1A1LMNAPOLB
	SCHEMBL2461002	0.80	POLB (0.48)	RXFP1TDP1KDM4EALDH1A1LMNA
	SCHEMBL2584398	0.80	POLB (0.43)	RXFP1KDM4EALDH1A1LMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.