SCHEMBL2461255

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2460912	0.96	RXFP1 (0.41)	POLBMAPK1LMNAALDH1A1KDM4E
	SCHEMBL2579066	0.89	POLB (0.44)	POLBMMP2MMP8MMP12MMP13
	SCHEMBL12175863	0.86	POLB (0.45)	POLBMMP2MMP8MMP12MMP13
	SCHEMBL2578644	0.85	ESR1 (0.42)	POLBALDH1A1KDM4EGAARXFP1
	SCHEMBL2461002	0.84	POLB (0.48)	POLBMMP2MMP8MMP12MMP13
	SCHEMBL2584398	0.83	POLB (0.43)	POLBMMP2MMP8MMP12MMP13
	SCHEMBL7910678	0.83	RAB9A (0.40)	POLBMAPK1LMNAALDH1A1GAA
	SCHEMBL7909989	0.81	ESR1 (0.39)	—
	Hydrochloric Acid SCHEMBL2578962	0.81	ESR1 (0.38)	—
	SCHEMBL2460946	0.80	POLB (0.43)	POLBALDH1A1KDM4EGAATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.