SCHEMBL2578644

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL7910678	0.91	RAB9A (0.40)	ESR1ESR2CLK1RAB9ACNR1
	SCHEMBL2586745	0.87	ESR1 (0.36)	ESR1ESR2CLK1RAB9ACNR1
	SCHEMBL2586348	0.87	ESR1 (0.37)	ESR1ESR2EDNRACLK1RAB9A
	SCHEMBL2581042	0.86	ESR1 (0.37)	ESR1ESR2EDNRACLK1RAB9A
	SCHEMBL2586818	0.86	ESR1 (0.34)	ESR1ESR2CNR1CNR2
	SCHEMBL3362491	0.85	ESR1 (0.38)	ESR1ESR2EDNRACLK1RAB9A
	SCHEMBL2461255	0.85	POLB (0.44)	KDM4EALDH1A1GAAPOLBRXFP1
	SCHEMBL2460912	0.84	RXFP1 (0.41)	KDM4EALDH1A1GAAPOLBRXFP1
	SCHEMBL12160478	0.84	ESR1 (0.38)	ESR1ESR2EDNRACLK1RAB9A
	SCHEMBL2464402	0.83	ESR1 (0.33)	ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.