⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6776556 | 0.86 | ALDH1A1 (0.44) | — | |
| SCHEMBL6261483 | 0.85 | NFKB1 (0.48) | — | |
| SCHEMBL6382813 | 0.83 | GPR84 (0.50) | — | |
| SCHEMBL11624224 | 0.83 | GPR84 (0.50) | — | |
| SCHEMBL11692251 | 0.83 | GPR84 (0.50) | — | |
| SCHEMBL11689543 | 0.83 | GPR84 (0.50) | — | |
| SCHEMBL6294221 | 0.83 | GPR84 (0.50) | — | |
| SCHEMBL10906089 | 0.83 | GPR84 (0.50) | — | |
| SCHEMBL11692164 | 0.83 | GPR84 (0.50) | — | |
| SCHEMBL10947381 | 0.83 | GPR84 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110869374-B | 2-oxo-1, 3-oxazolidinyl imidazothiadiazole derivatives | UCB生物制药有限责任公司 | 2022-08-30 | — | — | CN | disclosed |
| CN-110869375-B | 2-oxo-1-imidazolidinylimidazothiadiazole derivatives | UCB生物制药有限责任公司 | 2022-08-30 | — | — | CN | disclosed |
| US-11155565-B2 | 2-oxo-1,3-oxazolidinyl imidazothiadiazole derivatives | UCB Biopharma SRL | 2021-10-26 | — | — | US | disclosed |
| US-20200231599-A1 | 2-OXO-1,3-OXAZOLIDINYL IMIDAZOTHIADIAZOLE DERIVATIVES | UCB BIOPHARMA SPRL (BE) | 2020-07-23 | — | — | US | disclosed |
| CN-102892505-B | Chiral heterogeneous catalyst for asymmetric nitroaldol reaction | COUNCIL SCIENT IND RES | 2015-02-11 | — | — | CN | disclosed |
| US-8557726-B2 | Chiral heterogeneous catalyst for assymmetric nitroaldol reaction | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2013-10-15 | — | — | US | disclosed |
| US-20130096333-A1 | Chiral Heterogeneous Catalyst for Assymmetric Nitroaldol Reaction | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2013-04-18 | — | — | US | disclosed |
| CN-102892505-A | Chiral heterogeneous catalyst for asymmetric nitroaldol reaction | COUNCIL SCIENT IND RES | 2013-01-23 | — | — | CN | disclosed |
| EP-2544818-A1 | CHIRAL HETEROGENEOUS CATALYST FOR ASYMMETRIC NITROALDOL REACTION | Council of Scientific & Industrial Research (IN) | 2013-01-16 | — | — | EP | disclosed |
| CN-102458581-A | N- (hetero) aryl-pyrrolidine derivatives of pyrazol-4-yl-pyrrolo [2,3-d ] pyrimidines and pyrrol-3-yl-pyrrolo [2,3-d ] pyrimidines as JANUS kinase inhibitors | INCYTE CORP | 2012-05-16 | — | — | CN | disclosed |
| WO-2011110895-A1 | CHIRAL HETEROGENEOUS CATALYST FOR ASYMMETRIC NITROALDOL REACTION | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2011-09-15 | — | — | WO | disclosed |
| US-4581178-A | USING TRANSITION METAL COMPLEXES CONTAINING PHOSPHINE OR ARSINE LI | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-04-08 | — | — | US | disclosed |
| EP-0024113-B1 | STABILISATION OF 1,1,1,-TRICHLOROETHANE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1983-11-09 | — | — | EP | disclosed |
| US-4356038-A | TERT-BUTANOL, NITROMETHANE, NITROPROPANE OR NITROETHANE | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1982-10-26 | — | — | US | disclosed |
| EP-0024113-A1 | Stabilisation of 1,1,1,-trichloroethane | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1981-02-25 | — | — | EP | disclosed |
| US-4058541-A | Preparation of 2-alkanoyloxy-alkanoic | TEXACO INC. (US) | 1977-11-15 | — | — | US | disclosed |
| US-4058540-A | FROM A NITROALKYL NITRATE OR NITRO ALCOHOL AND ALKANOIC ACID, CALCIUM OCIDE OR CARBOXYLATE CATALYST | TEXACO INC. (US) | 1977-11-15 | — | — | US | disclosed |
| US-4040977-A | HALOACETAMIDE OR THIOCYANOACETAMIDE-ALCOHOL-FORMALDEHYDE CONDENSATES | STERLING DRUG INC. (US) | 1977-08-09 | — | — | US | disclosed |