Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.43 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.43 |
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | LAP3 | P28838 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11692164 | 1.00 | GPR84 (0.50) | GPR84FFAR1FFAR4ALDH1A1NFKB1 | |
| SCHEMBL6382813 | 1.00 | GPR84 (0.50) | GPR84FFAR1FFAR4ALDH1A1NFKB1 | |
| SCHEMBL10906089 | 1.00 | GPR84 (0.50) | GPR84FFAR1FFAR4ALDH1A1NFKB1 | |
| SCHEMBL11624224 | 1.00 | GPR84 (0.50) | GPR84FFAR1FFAR4ALDH1A1NFKB1 | |
| SCHEMBL10947381 | 1.00 | GPR84 (0.50) | GPR84FFAR1FFAR4ALDH1A1NFKB1 | |
| SCHEMBL11689543 | 1.00 | GPR84 (0.50) | GPR84FFAR1FFAR4ALDH1A1NFKB1 | |
| SCHEMBL11692251 | 1.00 | GPR84 (0.50) | GPR84FFAR1FFAR4ALDH1A1NFKB1 | |
| SCHEMBL6261483 | 0.98 | NFKB1 (0.48) | GPR84FFAR1FFAR4ALDH1A1NFKB1 | |
| SCHEMBL6776556 | 0.92 | ALDH1A1 (0.44) | GPR84FFAR1FFAR4ALDH1A1NFKB1 | |
| SCHEMBL11877387 | 0.86 | ALDH1A1 (0.40) | GPR84FFAR1FFAR4ALDH1A1NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050222253-A1 | Anti-cancer nitro- and thia-fatty acids | FERRANTE ANTONIO | 2005-10-06 | — | — | US | disclosed |
| US-20050176815-A1 | Anti-inflammatory nitro-and thia-fatty acids | FERRANTE ANTONIO (AU) | 2005-08-11 | — | — | US | disclosed |
| US-20050176817-A1 | Anti-inflammatory nitro- and thia- fatty acids | FERRANTE ANTONIO (AU) | 2005-08-11 | — | — | US | disclosed |
| US-20050176816-A1 | Anti-inflammatory nitro- and thia-fatty acids | FERRANTE ANTONIO (AU) | 2005-08-11 | — | — | US | disclosed |
| US-6924309-B2 | Anti-inflammatory nitro and thia-fatty acids | CHILDREN, YOUTH AND WOMEN'S HEALTH SERVICE INCORPORATED (AU) | 2005-08-02 | — | — | US | disclosed |
| US-20040254240-A1 | Anti-cancer nitro- and thia-fatty acids | FERRANTE ANTONIO (AU) | 2004-12-16 | — | — | US | disclosed |
| EP-1218333-A4 | ANTI-INFLAMMATORY NITRO- AND THIA- FATTY ACIDS | WOMENS & CHILDRENS HOSPITAL (AU) | 2003-07-09 | — | — | EP | disclosed |
| EP-1218000-A4 | ANTI-CANCER NITRO- AND THIA-FATTY ACIDS | WOMENS & CHILDRENS HOSPITAL (AU) | 2003-07-09 | — | — | EP | disclosed |
| US-20030092762-A1 | Anti-inflammatory nitro and thia-fatty acids | PEPLIN BIOLIPIDS PTY LTD (AU) | 2003-05-15 | — | — | US | disclosed |
| US-20030078299-A1 | Anti-cancer nitro- and thia-fatty acids | CHILDREN, YOUTH AND WOMEN'S HEALTH SERVICE INCORPORATED (AU) | 2003-04-24 | — | — | US | disclosed |
| EP-1218000-A1 | ANTI-CANCER NITRO- AND THIA-FATTY ACIDS | WOMEN'S AND CHILDREN'S HOSPITAL (AU) | 2002-07-03 | — | — | EP | disclosed |
| EP-1218333-A1 | ANTI-INFLAMMATORY NITRO- AND THIA- FATTY ACIDS | WOMEN'S AND CHILDREN'S HOSPITAL (AU) | 2002-07-03 | — | — | EP | disclosed |
| WO-2001021575-A1 | ANTI-INFLAMMATORY NITRO- AND THIA- FATTY ACIDS | WOMEN'S AND CHILDREN'S HOSPITAL ADELAIDE (AU) | 2001-03-29 | — | — | WO | disclosed |
| WO-2001021172-A1 | ANTI-CANCER NITRO- AND THIA-FATTY ACIDS | WOMEN'S AND CHILDREN'S HOSPITAL ADELAIDE (AU) | 2001-03-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040254240-A1 | Anti-cancer nitro- and thia-fatty acids | ALOX5, ALOX15, ALOX12 | GPR84 1041/4885FFAR1 177/4885FFAR4 458/4885 |
| US-20030078299-A1 | Anti-cancer nitro- and thia-fatty acids | ALOX5, ALOX15, ALOX12 | GPR84 877/4885FFAR1 158/4885FFAR4 392/4885 |
| US-20050176815-A1 | Anti-inflammatory nitro-and thia-fatty acids | PTGES, PTGES2, ALOX5 | GPR84 992/4885FFAR1 163/4885FFAR4 352/4885 |
| US-20050222253-A1 | Anti-cancer nitro- and thia-fatty acids | ALOX5, ALOX15, ALOX12 | GPR84 890/4885FFAR1 288/4885FFAR4 705/4885 |
| US-20050176817-A1 | Anti-inflammatory nitro- and thia- fatty acids | PTGES, PTGES2, ALOX5 | GPR84 992/4885FFAR1 163/4885FFAR4 352/4885 |
| US-20030092762-A1 | Anti-inflammatory nitro and thia-fatty acids | PTGES2, PTGES, PTGS2 | GPR84 1262/4885FFAR1 188/4885FFAR4 369/4885 |
| US-20050176816-A1 | Anti-inflammatory nitro- and thia-fatty acids | PTGES, PTGES2, ALOX5 | GPR84 992/4885FFAR1 163/4885FFAR4 352/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.