SCHEMBL24612935

SCHEMBL24612935

Cc1ccccc1-c1ccc(C2=CC=CCC2)cc1N

nearest known ligand 0.33

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CTSD P07339 1/20 0.33
BACE1 P56817 1/20 0.33
ADORA1 P30542 1/20 0.33
ALOX5AP P20292 1/20 0.32
FEN1 P39748 1/20 0.32
CD274 Q9NZQ7 1/20 0.32
LCK P06239 1/20 0.32
KDR P35968 1/20 0.32
JAK3 P52333 1/20 0.32
MAPK14 Q16539 1/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC2 Q92769 1/20 0.32
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31
DHFR P00374 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27254459 0.78 CTSD (0.30) CTSDBACE1
SCHEMBL20808856 0.74 HEXA (0.35) CA1CA2CA9
SCHEMBL21254354 0.71 L3MBTL1 (0.36) CA12CA1CA2CA9
SCHEMBL10287421 0.71 ALDH1A1 (0.44)
SCHEMBL27313792 0.69 TP53 (0.31)
SCHEMBL22780781 0.69 ALDH1A1 (0.39)
SCHEMBL23966394 0.69 CYP3A4 (0.42)
SCHEMBL25633943 0.69 ALDH1A1 (0.39)
SCHEMBL17355636 0.69 CYP3A4 (0.42) CA12CA1CA2CA9
SCHEMBL29407620 0.69 ACHE (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4026839-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE Samsung Electronics Co., Ltd. (KR) 2022-07-13 EP disclosed