Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.34 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | CDC14B | O60729 | 2/20 | 0.34 |
| ▸ | CDC14A | Q9UNH5 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24614767 | 0.91 | KDM4E (0.37) | KDM4EKMT2AMEN1ALDH1A1RAB9A | |
| SCHEMBL24614765 | 0.91 | CA1 (0.35) | KDM4EKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL24614721 | 0.89 | PLA2G2A (0.38) | KDM4EKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL24614786 | 0.88 | MAPT (0.38) | KDM4EKMT2AMEN1ALDH1A1RAB9A | |
| SCHEMBL24614754 | 0.87 | PLA2G2A (0.40) | KDM4EKMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL24614908 | 0.87 | PLA2G2A (0.40) | KDM4EKMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL24614755 | 0.87 | PLA2G2A (0.40) | KDM4EKMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL24614703 | 0.87 | CDC14B (0.36) | GPR84KDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL24614791 | 0.87 | CA1 (0.38) | GPR84KDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL24474566 | 0.87 | CA1 (0.39) | KDM4EKMT2AMEN1ALDH1A1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220223801-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2022-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220223801-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | TMEM109, PIEZO1, L1CAM | GPR84 3746/4885SOS1 2072/4885KDM4E 3297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.