Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24614786 | 0.93 | MAPT (0.38) | KDM4EHPGDTDP1MAPTTSHR | |
| SCHEMBL24614906 | 0.91 | KDM4E (0.37) | KDM4EHPGDTDP1MAPTTSHR | |
| SCHEMBL24614726 | 0.91 | GPR84 (0.34) | KDM4EHPGDTDP1MAPTTSHR | |
| SCHEMBL24614644 | 0.91 | KDM4E (0.33) | KDM4EHPGDTDP1MAPTTSHR | |
| SCHEMBL24614943 | 0.90 | GPR84 (0.38) | KDM4EHPGDTDP1MAPTTSHR | |
| SCHEMBL24614765 | 0.90 | CA1 (0.35) | KDM4EHPGDTDP1MAPTTSHR | |
| SCHEMBL24614703 | 0.89 | CDC14B (0.36) | KDM4EHPGDTDP1MAPTTSHR | |
| SCHEMBL24614791 | 0.89 | CA1 (0.38) | KDM4EHPGDMAPTTSHRHSD17B10 | |
| SCHEMBL24474566 | 0.89 | CA1 (0.39) | KDM4EHPGDTDP1MAPTTSHR | |
| SCHEMBL24614646 | 0.88 | HPGD (0.38) | KDM4EHPGDTDP1MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023139034-A1 | ORGANIC ELECTRIC ELEMENT WITH MIXED HOST SYSTEM | MERCK PATENT GMBH (DE) | 2023-07-27 | — | — | WO | disclosed |
| US-20220223801-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2022-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220223801-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | TMEM109, PIEZO1, L1CAM | KDM4E 3297/4885HPGD 1079/4885TDP1 1970/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.