Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.32 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.32 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29398715 | 1.00 | FFAR4 (0.36) | FFAR4KMT2AALDH1A1POLBGAA | |
| SCHEMBL24616779 | 0.85 | HCAR2 (0.37) | HCAR2 | |
| SCHEMBL24616783 | 0.82 | KMT2A (0.48) | KMT2AALDH1A1POLBGAATHRB | |
| SCHEMBL24616741 | 0.77 | HCAR2 (0.32) | HCAR2 | |
| SCHEMBL24616699 | 0.75 | HCAR2 (0.36) | KMT2AALDH1A1GAATHRBHDAC3 | |
| SCHEMBL24616793 | 0.75 | HSD11B1 (0.38) | KMT2AALDH1A1THRBHCAR2 | |
| SCHEMBL24616796 | 0.75 | AKR1C3 (0.31) | HCAR2 | |
| SCHEMBL24616777 | 0.74 | HCAR2 (0.33) | ALDH1A1HCAR2 | |
| SCHEMBL24616696 | 0.74 | SLC6A2 (0.35) | NOTUMHCAR2 | |
| SCHEMBL29395638 | 0.74 | SLC6A2 (0.35) | NOTUMHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022038365-A9 | FUMARATE DERIVATIVES AND THEIR MEDICAL USE | SITRYX THERAPEUTICS LIMITED (GB) | 2022-07-14 | — | — | WO | disclosed |