Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.37 |
| ▸ | CCR2 | P41597 | 1/20 | 0.31 |
| ▸ | TPMT | P51580 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.30 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.30 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29398715 | 0.85 | FFAR4 (0.36) | HCAR2 | |
| SCHEMBL24616769 | 0.85 | FFAR4 (0.36) | HCAR2 | |
| SCHEMBL24616793 | 0.85 | HSD11B1 (0.38) | HCAR2CCR2 | |
| SCHEMBL24616741 | 0.85 | HCAR2 (0.32) | HCAR2 | |
| SCHEMBL24616777 | 0.81 | HCAR2 (0.33) | HCAR2 | |
| SCHEMBL24616699 | 0.80 | HCAR2 (0.36) | HCAR2 | |
| SCHEMBL24394123 | 0.80 | CCR2 (0.32) | CCR2 | |
| SCHEMBL29588392 | 0.80 | CCR2 (0.32) | CCR2 | |
| SCHEMBL24616796 | 0.77 | AKR1C3 (0.31) | HCAR2AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL24616690 | 0.77 | ALDH1A1 (0.38) | HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022038365-A9 | FUMARATE DERIVATIVES AND THEIR MEDICAL USE | SITRYX THERAPEUTICS LIMITED (GB) | 2022-07-14 | — | — | WO | claimed |
| WO-2022038365-A9 | FUMARATE DERIVATIVES AND THEIR MEDICAL USE | SITRYX THERAPEUTICS LIMITED (GB) | 2022-07-14 | — | — | WO | disclosed |
| WO-2022038365-A9 | FUMARATE DERIVATIVES AND THEIR MEDICAL USE | SITRYX THERAPEUTICS LIMITED (GB) | 2022-07-14 | — | — | WO | disclosed |