Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | CCR1 | P32246 | 2/20 | 0.44 |
| ▸ | CCR8 | P51685 | 2/20 | 0.44 |
| ▸ | SLC40A1 | Q9NP59 | 3/20 | 0.43 |
| ▸ | TOP1 | P11387 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28275870 | 0.83 | L3MBTL1 (0.66) | KDM4EL3MBTL1RAB9ANPC1CCR1 | |
| SCHEMBL1148265 | 0.81 | CCR1 (0.50) | KDM4EL3MBTL1CCR1CCR8SLC40A1 | |
| SCHEMBL24619598 | 0.76 | CCR1 (0.43) | KDM4EL3MBTL1RAB9ANPC1CCR1 | |
| SCHEMBL24619115 | 0.76 | ADORA2A (0.41) | KDM4EL3MBTL1RAB9ANPC1CCR1 | |
| SCHEMBL9275208 | 0.75 | SLC40A1 (0.50) | KDM4EL3MBTL1RAB9ANPC1CCR1 | |
| SCHEMBL24619738 | 0.75 | RPS6KA5 (0.42) | KDM4EL3MBTL1RAB9ANPC1CCR1 | |
| SCHEMBL10784946 | 0.73 | NPC1 (0.78) | KDM4ERAB9ANPC1ALDH1A1NR4A2 | |
| SCHEMBL25523414 | 0.72 | KDM4E (0.51) | KDM4EL3MBTL1RAB9ANPC1ADORA3 | |
| SCHEMBL29720513 | 0.71 | ALDH1A1 (0.63) | KDM4EL3MBTL1CCR1CCR8TOP1 | |
| SCHEMBL8117455 | 0.71 | TOP1 (0.47) | KDM4EL3MBTL1RAB9ANPC1CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010094643-A1 | QUINOLINE DERIVATIVES AND THEIR USES FOR RHINITIS AND URTICARIA | GLAXO GROUP LIMITED (GB) | 2010-08-26 | — | — | WO | disclosed |