Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 4/20 | 0.43 |
| ▸ | CCR8 | P51685 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | CCR5 | P51681 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24619115 | 0.77 | ADORA2A (0.41) | CCR1CCR8L3MBTL1CCR5ALDH1A1 | |
| SCHEMBL3718956 | 0.76 | KDM4E (0.46) | CCR1CCR8L3MBTL1CCR5ALDH1A1 | |
| SCHEMBL24619738 | 0.73 | RPS6KA5 (0.42) | CCR1CCR8L3MBTL1CCR5ALDH1A1 | |
| SCHEMBL1148265 | 0.73 | CCR1 (0.50) | CCR1CCR8L3MBTL1CCR5ALDH1A1 | |
| SCHEMBL21223238 | 0.73 | MAP4K4 (0.40) | L3MBTL1ALDH1A1ADORA1SMN1; SMN2NPC1 | |
| SCHEMBL28275870 | 0.72 | L3MBTL1 (0.66) | CCR1CCR8L3MBTL1CCR5ADORA2A | |
| SCHEMBL24619110 | 0.71 | ADORA2A (0.46) | L3MBTL1ADORA2AADORA3ADORA1KDM4E | |
| SCHEMBL29727041 | 0.71 | ADORA2A (0.46) | L3MBTL1ADORA2AADORA3ADORA1KDM4E | |
| SCHEMBL9275208 | 0.70 | SLC40A1 (0.50) | CCR1CCR8L3MBTL1CCR5ALDH1A1 | |
| SCHEMBL9931109 | 0.70 | MAP4K4 (0.41) | TP53SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022149057-A1 | CDK INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2022-07-14 | — | — | WO | disclosed |