Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.34 |
| ▸ | NMT2 | O60551 | 2/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.33 |
| ▸ | NMT1 | P30419 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 5/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19935419 | 0.83 | GPR35 (0.67) | GPR35LMNATDP1MEN1KMT2A | |
| SCHEMBL25472686 | 0.80 | GPR35 (0.60) | GPR35LMNATDP1MEN1KMT2A | |
| SCHEMBL22422557 | 0.77 | GPR35 (0.69) | GPR35LMNATDP1MEN1KMT2A | |
| SCHEMBL22422556 | 0.76 | GPR35 (0.56) | GPR35LMNATDP1MEN1KMT2A | |
| SCHEMBL26848548 | 0.74 | MEN1 (0.55) | GPR35LMNATDP1MEN1KMT2A | |
| SCHEMBL19925831 | 0.74 | GPR35 (0.64) | GPR35LMNATDP1MEN1KMT2A | |
| SCHEMBL24310283 | 0.74 | GPR35 (0.53) | GPR35LMNATDP1MEN1KMT2A | |
| SCHEMBL19935421 | 0.73 | GPR35 (0.48) | GPR35LMNATDP1MEN1KMT2A | |
| SCHEMBL19935430 | 0.73 | GPR35 (0.52) | GPR35LMNATDP1MEN1KMT2A | |
| SCHEMBL25472689 | 0.71 | TDP1 (0.47) | GPR35LMNATDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220218652-A1 | METHODS OF TREATING CYTOKINE RELEASE SYNDROME | AZTHERAPIES, INC. | 2022-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220218652-A1 | METHODS OF TREATING CYTOKINE RELEASE SYNDROME | CMKLR1, CMKLR2, GSS | GPR35 393/4885LMNA 3211/4885TDP1 3763/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.