SCHEMBL2462001

SCHEMBL2462001

CC(C(=O)O)=C(Cl)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.50
DAO P14920 1/20 0.50
NAPRT Q6XQN6 1/20 0.50
CES2 O00748 6/20 0.48
CES1 P23141 6/20 0.48
ALDH1A1 P00352 4/20 0.44
HIF1A Q16665 2/20 0.44
SRD5A2 P31213 1/20 0.43
AKR1C1 Q04828 1/20 0.42
TRPA1 O75762 1/20 0.41
MAPK1 P28482 1/20 0.41
GSK3B P49841 1/20 0.41
MAPT P10636 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
KDM4E B2RXH2 1/20 0.41
MEN1 O00255 1/20 0.41
NPC1 O15118 1/20 0.41
GLA P06280 1/20 0.41
RAB9A P51151 1/20 0.41
KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2461997 1.00 TSHR (0.50) TSHRDAONAPRTCES2CES1
SCHEMBL1232452 0.78 CES1 (0.54) TSHRDAONAPRTCES2CES1
SCHEMBL367453 0.78 CES1 (0.54) TSHRDAONAPRTCES2CES1
SCHEMBL367456 0.78 CES1 (0.54) TSHRDAONAPRTCES2CES1
SCHEMBL6527794 0.77 CES1 (0.48) TSHRDAONAPRTCES2CES1
SCHEMBL6527803 0.77 CES1 (0.48) TSHRDAONAPRTCES2CES1
SCHEMBL1562534 0.76 CES1 (0.52) TSHRDAONAPRTCES2CES1
SCHEMBL1562541 0.76 CES1 (0.52) TSHRDAONAPRTCES2CES1
SCHEMBL585335 0.76 CES1 (0.52) TSHRDAONAPRTCES2CES1
SCHEMBL5072437 0.76 CES1 (0.52) TSHRDAONAPRTCES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9527997-B2 Polyorganosiloxane-containing graft copolymer, resin composition, and molded article MITSUBISHI RAYON CO., LTD. (JP) 2016-12-27 US disclosed
CN-104205404-B Organic luminescent device and for the manufacture of organic light-emitting device method OSRAM OPTO SEMICONDUCTORS GMBH (DE) 2016-05-18 CN disclosed
CN-102428523-B Electrically sheet material and manufacture method thereof LG HAUSYS, LTD. (KR) 2016-04-13 CN disclosed
US-20150267048-A1 Polyorganosiloxane-Containing Graft Copolymer, Resin Composition, and Molded Article MITSUBISHI RAYON CO., LTD. (JP) 2015-09-24 US disclosed
CN-104205404-A Organic light-emitting device and method for producing organic light-emitting part OSRAM OPTO SEMICONDUCTORS GMBH 2014-12-10 CN disclosed
US-8729205-B2 Flowability improver for engineering plastics, thermoplastic resin compositions containing the same and molded articles of the compositions MITSUBISHI RAYON CO., LTD. (JP) 2014-05-20 US disclosed
US-8202943-B2 Fluidity-improving agent, aromatic polycarbonate resin composition, and shaped article thereof MITSUBISHI RAYON CO., LTD. (JP) 2012-06-19 US disclosed
CN-102428523-A Conductive flooring material and method for producing same LG HAUSYS LTD 2012-04-25 CN disclosed
US-8012668-B2 Planographic printing plate precursor FUJIFILM CORPORATION (JP) 2011-09-06 US disclosed
US-20100029855-A1 FLUIDITY-IMPROVING AGENT, AROMATIC POLYCARBONATE RESIN COMPOSITION, AND SHAPED ARTICLE THEREOF MITSUBISHI RAYON CO., LTD (JP) 2010-02-04 US disclosed
US-20080206675-A1 Support with hydrophilic polymer bonded to support by crosslinking and image forming layer FUJIFILM CORPORATION (JP) 2008-08-28 US disclosed
EP-1577087-B1 Planographic printing plate precursor FUJI PHOTO FILM CO LTD (JP) 2007-01-17 EP disclosed
US-20060246372-A1 Planographic printing plate precursor FUJI PHOTO FILM CO., LTD. 2006-11-02 US disclosed
EP-1577087-A2 Planographic printing plate precursor Fuji Photo Film Co. Ltd. (JP) 2005-09-21 EP disclosed