Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 5/20 | 0.48 |
| ▸ | CES2 | O00748 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA4 | P22748 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6527794 | 1.00 | CES1 (0.48) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL1232452 | 0.78 | CES1 (0.54) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL367456 | 0.78 | CES1 (0.54) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL367453 | 0.78 | CES1 (0.54) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL2462001 | 0.77 | TSHR (0.50) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL2461997 | 0.77 | TSHR (0.50) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL1562534 | 0.76 | CES1 (0.52) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL5072437 | 0.76 | CES1 (0.52) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL1562541 | 0.76 | CES1 (0.52) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL29319502 | 0.76 | CES1 (0.48) | CES1CES2TSHRALDH1A1DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005109041-A1 | COMPOSITIONS FOR USE IN THE MANUFACTURE OF LENSES | MEDICAL POLYMERS LIMITED (GB) | 2005-11-17 | — | — | WO | disclosed |