Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | COMT | P21964 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 4/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 3/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23957471 | 0.85 | HCAR2 (0.45) | COMTESR1KCNH2HPGDTSHR | |
| SCHEMBL13495125 | 0.75 | L3MBTL1 (0.47) | COMTESR1KCNH2HPGDTSHR | |
| SCHEMBL24622014 | 0.74 | KCNH2 (0.43) | COMTESR1KCNH2HPGDGAA | |
| SCHEMBL17617764 | 0.71 | ESR1 (0.42) | ESR1KCNH2HPGDTSHRGAA | |
| SCHEMBL23189126 | 0.70 | HCAR3 (0.45) | ESR1KCNH2MAPTDAO | |
| SCHEMBL64650 | 0.68 | BACE1 (0.49) | ESR1KCNH2ALDH1A1MAPTDAO | |
| SCHEMBL15003 | 0.68 | TSHR (0.52) | HPGDTSHRALDH1A1MAPTTDP1 | |
| SCHEMBL17622583 | 0.68 | KCNH2 (0.43) | COMTESR1KCNH2HPGDTSHR | |
| SCHEMBL18198235 | 0.67 | HPGD (0.51) | COMTHPGDTSHRALDH1A1DAO | |
| SCHEMBL27768180 | 0.67 | RAB9A (0.52) | ESR1KCNH2HPGDGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11793823-B2 | Compounds and pharmaceutical uses thereof | SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) | 2023-10-24 | — | — | US | disclosed |
| US-11793823-B2 | Compounds and pharmaceutical uses thereof | SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) | 2023-10-24 | — | — | US | disclosed |
| US-20220218730-A1 | COMPOUNDS AND PHARMACEUTICAL USES THEREOF | SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) | 2022-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220218730-A1 | COMPOUNDS AND PHARMACEUTICAL USES THEREOF | HRH4, OR10J3, CYP3A5 | COMT 1039/4885ESR1 2846/4885KCNH2 252/4885 |
| US-11793823-B2 | Compounds and pharmaceutical uses thereof | HRH4, OR10J3, CYP3A5 | COMT 1039/4885ESR1 2846/4885KCNH2 252/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.