Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | UBE2N | P61088 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL405842 | 0.78 | — | — | |
| SCHEMBL26129059 | 0.78 | — | — | |
| SCHEMBL26127317 | 0.78 | CCR1 (0.44) | DYRK1A | |
| SCHEMBL1673128 | 0.78 | — | — | |
| SCHEMBL2458453 | 0.75 | CCR1 (0.41) | MEN1POLBKMT2A | |
| SCHEMBL26129630 | 0.74 | IMPDH2 (0.35) | — | |
| SCHEMBL26128744 | 0.74 | IDO1 (0.33) | — | |
| SCHEMBL26128856 | 0.74 | MITF (0.32) | GAAKMT2A | |
| SCHEMBL16401213 | 0.72 | KDM4E (0.31) | GAA | |
| SCHEMBL20416853 | 0.72 | ADORA2A (0.67) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2053049-B1 | Preparation of 2' , 6' -di-pyrazolyl-pyridine containing a reactive group R in 4' position | KARLSRUHER INST TECHNOLOGIE (DE) | 2011-09-21 | — | — | EP | disclosed |
| EP-2053049-A1 | Preparation of 2' , 6' -di-pyrazolyl-pyridine containing a reactive group R in 4' position | Forschungszentrum Karlsruhe GmbH (DE) | 2009-04-29 | — | — | EP | disclosed |