Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1673128 | 0.76 | — | — | |
| SCHEMBL2462292 | 0.72 | DYRK1A (0.30) | GAA | |
| SCHEMBL15720345 | 0.69 | TP53 (0.59) | — | |
| SCHEMBL28466328 | 0.68 | ALPL (0.58) | NPC1 | |
| SCHEMBL168659 | 0.68 | POLB (0.61) | GAA | |
| SCHEMBL1593197 | 0.68 | PIN1 (0.56) | KDM4ENPC1HSD17B10 | |
| SCHEMBL30040683 | 0.68 | PIN1 (0.56) | KDM4ENPC1HSD17B10 | |
| SCHEMBL644755 | 0.68 | ADORA2A (0.40) | KDM4ENPC1GAAHSD17B10 | |
| SCHEMBL643407 | 0.68 | ADORA3 (0.34) | NPC1 | |
| SCHEMBL28313237 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160326159-A1 | HETEROARYL SUBSTITUTED PYRAZOLES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-11-10 | — | — | US | claimed |
| EP-3004097-A1 | KINASE INHIBITORS | Chiesi Farmaceutici S.p.A. (IT) | 2016-04-13 | — | — | EP | disclosed |
| WO-2014195402-A1 | KINASE INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2014-12-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160326159-A1 | HETEROARYL SUBSTITUTED PYRAZOLES | CYP3A43, CYP2C19, CYP3A7 | KDM4E 4061/4885NPC1 156/4885GAA 268/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.