SCHEMBL24625815

SCHEMBL24625815

C(=N/Nc1nc(-c2ccc3ccccc3c2)cs1)\c1ccccc1

nearest known ligand 0.84

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ MAOA P21397 13/20 0.84
▸ MAOB P27338 12/20 0.84
▸ MEN1 O00255 2/20 0.65
▸ NPC1 O15118 2/20 0.65
▸ GAA P10253 2/20 0.65
▸ MAPT P10636 2/20 0.65
▸ RAB9A P51151 2/20 0.65
▸ KMT2A Q03164 2/20 0.65
▸ ALDH1A1 P00352 1/20 0.65
▸ SMN1; SMN2 Q16637 1/20 0.61
▸ AR P10275 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13186607 0.86 MAPT (0.84) MAOAMAOBMEN1NPC1GAA
SCHEMBL17150984 0.83 MAPT (0.76) MAOAMAOBMEN1NPC1GAA
SCHEMBL18980780 0.83 MAPT (0.76) MAOAMAOBMEN1NPC1GAA
SCHEMBL18980779 0.83 MAPT (0.76) MAOAMAOBMEN1NPC1GAA
SCHEMBL20956524 0.82 DHODH (0.80) MAOAMAOBNPC1GAARAB9A
SCHEMBL19631420 0.82 DHODH (0.80) MAOAMAOBNPC1GAARAB9A
SCHEMBL29911542 0.82 DHODH (0.80) MAOAMAOBNPC1GAARAB9A
SCHEMBL25613879 0.80 MAOA (0.71) MAOAMAOBGAAAR
SCHEMBL23996295 0.80 MAOA (0.68) MAOAMAOBGAAAR
SCHEMBL1068115 0.78 MAPT (0.74) MAOAMEN1NPC1GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230296820-A1 POLARIZING PLATE AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2023-09-21 — — US disclosed
US-11732191-B2 Compound, polymerizable composition, cured product, optical film, polarizing plate, and image display device FUJIFILM CORPORATION (JP) 2023-08-22 — — US disclosed
US-20230228928-A1 OPTICAL LAMINATE, POLARIZING PLATE, AND IMAGE DEVICE DISPLAY FUJIFILM CORPORATION (JP) 2023-07-20 — — US disclosed
US-20230183574-A1 LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL CURED LAYER, OPTICAL FILM, POLARIZING PLATE, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2023-06-15 — — US disclosed
US-20230143665-A1 FLUORINE-CONTAINING POLYMER, COMPOSITION, OPTICAL FILM, LIQUID CRYSTAL FILM, HARDCOAT FILM, AND POLARIZING PLATE FUJIFILM CORPORATION (JP) 2023-05-11 — — US disclosed
US-20230135489-A1 FLUORINE-CONTAINING COPOLYMER, COMPOSITION, OPTICAL FILM, LIQUID CRYSTAL FILM, HARDCOAT FILM, AND POLARIZING PLATE FUJIFILM CORPORATION (JP) 2023-05-04 — — US disclosed
US-20230130269-A1 LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL CURED LAYER, OPTICAL FILM, POLARIZING PLATE, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2023-04-27 — — US disclosed
US-20220220382-A1 LIQUID CRYSTAL COMPOSITION, OPTICALLY ANISOTROPIC LAYER, OPTICAL FILM, POLARIZING PLATE, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2022-07-14 — — US disclosed
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