SCHEMBL2462702

SCHEMBL2462702

Nc1cccc(O[PH](=O)c2ccccc2)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 4/20 0.53
CYP3A4 P08684 3/20 0.46
ALDH1A1 P00352 2/20 0.46
TP53 P04637 1/20 0.42
MAPT P10636 2/20 0.40
POLB P06746 1/20 0.40
HSP90AA1 P07900 1/20 0.40
MAOA P21397 4/20 0.39
CASP1 P29466 1/20 0.38
RECQL P46063 1/20 0.38
PBRM1 Q86U86 1/20 0.38
ATM Q13315 1/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
NLRP3 Q96P20 1/20 0.37
TSHR P16473 1/20 0.37
TDP1 Q9NUW8 2/20 0.36
CYP19A1 P11511 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL258694 0.80 LTA4H (0.39) MAOAATMKMT2ATSHRTDP1
SCHEMBL2461064 0.79 MAOA (0.48) MAOBCYP3A4ALDH1A1MAPTMAOA
SCHEMBL3117307 0.79 ALDH1A1 (0.54) MAOBCYP3A4ALDH1A1TP53MAPT
SCHEMBL258562 0.78 LTA4H (0.38) MAOATSHRTDP1
SCHEMBL29243926 0.78 LTA4H (0.38) MAOATSHRTDP1
SCHEMBL23535205 0.78 LTA4H (0.38) MAOATSHRTDP1
Hydrochloric Acid SCHEMBL28669301 0.78 LTA4H (0.38) MAOATSHRTDP1
SCHEMBL258508 0.78 LTA4H (0.38) MAOATSHRTDP1
SCHEMBL258611 0.78 LTA4H (0.38) MAOATSHRTDP1
SCHEMBL258700 0.78 LTA4H (0.38) MAOATSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8476824-B2 Active matrix organic electroluminescent device and method of manufacture thereof UNIVERSITY OF ELECTRONIC SCIENCE AND TECHNOLOGY OF CHINA (CN) 2013-07-02 US disclosed
US-8278820-B2 Active matrix organic electroluminescent device and method of manufacture thereof University of Electric Sience and Technology of China (CN) 2012-10-02 US disclosed
US-20120164762-A1 Active matrix organic electroluminescent device and method of manufacture thereof UNIVERSITY OF ELECTRONIC SCIENCE AND TECHNOLOGY OF CHINA 2012-06-28 US disclosed
US-20110221331-A1 Active matrix organic electroluminescent device and method of manufacture thereof UNIVERSITY OF ELECTRONIC SCIENCE AND TECHNOLOGY OF CHINA 2011-09-15 US disclosed