SCHEMBL3117307

SCHEMBL3117307

Nc1cccc(O[PH](=O)Oc2cccc(N)c2)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.54
CYP3A4 P08684 3/20 0.54
MAOB P27338 2/20 0.52
TP53 P04637 1/20 0.48
ATM Q13315 1/20 0.46
CASP1 P29466 1/20 0.46
RECQL P46063 1/20 0.46
MAPT P10636 2/20 0.46
POLB P06746 1/20 0.46
HSP90AA1 P07900 1/20 0.46
TSHR P16473 2/20 0.42
APP P05067 1/20 0.41
MEN1 O00255 1/20 0.39
MITF O75030 1/20 0.39
GAA P10253 1/20 0.39
GFER P55789 1/20 0.39
KMT2A Q03164 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
NLRP1 Q9C000 1/20 0.39
NOD2 Q9HC29 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1961835 0.83 ALDH1A1 (0.50) ALDH1A1CYP3A4MAOBTP53ATM
SCHEMBL2462702 0.79 MAOB (0.53) ALDH1A1CYP3A4MAOBTP53ATM
SCHEMBL13412436 0.77 GSTP1 (0.38) ALDH1A1MAOBTSHRMEN1KMT2A
SCHEMBL6891791 0.77 F2 (0.32) ALDH1A1CYP3A4ATMMAPTMEN1
SCHEMBL20906852 0.75 ALDH1A1 (0.46) ALDH1A1CYP3A4MAOBTP53ATM
SCHEMBL3361603 0.74 SOD1 (0.49) ALDH1A1MAOBRECQLMAPTTSHR
SCHEMBL4092932 0.74 CYP3A4 (0.52) ALDH1A1CYP3A4POLBTSHRAPP
SCHEMBL11165839 0.74 WDR5 (0.46) ALDH1A1TSHRSMN1; SMN2LMNA
SCHEMBL31491517 0.74 ACHE (0.56) ALDH1A1MAPTGAAKMT2ASMN1; SMN2
SCHEMBL28437448 0.74 ACHE (0.50) ALDH1A1CYP3A4MAOBPOLBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240393684-A1 METHOD OF FORMING PATTERNS SAMSUNG SDI CO., LTD. (KR) 2024-11-28 US claimed
EP-0429614-B1 AZOPHENYL COMPOUNDS JAMES ROBINSON LTD (GB) 1995-10-11 EP claimed
EP-0429614-A1 AZOPHENYL COMPOUNDS. JAMES ROBINSON LTD (GB) 1991-06-05 EP claimed
WO-1990015850-A1 AZOPHENYL COMPOUNDS JAMES ROBINSON LIMITED (GB) 1990-12-27 WO claimed
US-4230618-A CELLULOSE ICI UNITED STATES, INC. (US) 1980-10-28 US claimed
US-20240393684-A1 METHOD OF FORMING PATTERNS SAMSUNG SDI CO., LTD. (KR) 2024-11-28 US disclosed
CN-114685797-A Water reducing agent containing carboxyl and phosphonic acid group and preparation method thereof 南京博特新材料有限公司 2022-07-01 CN disclosed
US-9920083-B2 Image recording paper medium and image recording method FUJIFILM CORPORATION (JP) 2018-03-20 US disclosed
US-20160250866-A1 IMAGE RECORDING PAPER MEDIUM AND IMAGE RECORDING METHOD FUJIFILM CORPORATION (JP) 2016-09-01 US disclosed
EP-2345636-B1 CASR AGONIST AJINOMOTO KK (JP) 2016-03-30 EP disclosed
US-8796485-B2 CaSR agonists AJINOMOTO CO., INC. (JP) 2014-08-05 US disclosed
EP-1801170-B1 Inkjet ink for preparing lithographic printing plates and method for their preparation AGFA GRAPHICS NV (BE) 2010-04-07 EP disclosed
EP-0429614-A1 AZOPHENYL COMPOUNDS. JAMES ROBINSON LTD (GB) 1991-06-05 EP disclosed
WO-1990015850-A1 AZOPHENYL COMPOUNDS JAMES ROBINSON LIMITED (GB) 1990-12-27 WO disclosed
US-4472308-A Azo dyestuffs containing an amino or acylated amino naphthol monosulfonic acid radical and at least one reactive phosphoric or phosphonic acid group ICI UNITED STATES, INC. (US) 1984-09-18 US disclosed
US-4230618-A CELLULOSE ICI UNITED STATES, INC. (US) 1980-10-28 US disclosed
US-4225523-A Anthraquinone dyestuffs IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1980-09-30 US disclosed
US-4225491-A REACTIVE DYES FOR COTTON ICI UNITED STATES, INC. (US) 1980-09-30 US disclosed
US-4224024-A Process for the reactive dyeing and printing of fibrous materials containing hydroxy groups with a water-soluble organic dyestuff containing at least one phosphonic acid-monofluoride group and at least one ionic water-solubilizing group HOECHST AKTIENGESELLSCHAFT (DE) 1980-09-23 US disclosed
US-4134722-A Reactive dyeing system using phosphorus acid dyes with a cyanamide compound BURLINGTON INDUSTRIES, INC. (US) 1979-01-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160250866-A1 IMAGE RECORDING PAPER MEDIUM AND IMAGE RECORDING METHOD PHOSPHO1, ITPR2, PPIP5K2 ALDH1A1 4176/4885CYP3A4 4706/4885MAOB 1345/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.